ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
BMC Complement Altern Med.2014, 14:352Phytomedicine.2015, 22(14):1262-8Korean Journal of Pharmacognosy....2015...SBRAS2016, 12Mediators Inflamm. 2016, 2016:6189590Molecules.2016, 21(6)HortTechnology2016, 26(6):816-819Current Pharmaceutical Analysis...2017...
Evid Based Complement Alternat Me...2017...Invest New Drugs.2017, 35(2):166-179J Nat Med.2017, 71(2):380-388Oncotarget.2017, 8(64):108006-108019Appl Microbiol Biotechnol....2018...J Pharm Biomed Anal.2018, 151:32-41Anal Bioanal Chem....2018...Korean Journal of Pharmacognosy...2018...
Front Pharmacol.2019, 10:1226Cardiovasc Toxicol.2019, 19(4):297-305Journal of Apiculture...2019...Toxicol Res.2019, 35(4):371-387J Funct Foods2019, 54:449-456Anal Biochem.2019, 569:10-15J Mol Recognit.2020, 33(2):e2819
Our products had been exported to the following research institutions and universities, And still growing.
Mahidol University (Thailand)University of Dicle (Turkey)The Ohio State University (USA)Universidad de Antioquia (Colombia)
Molecular Biology Institute of ... (Spain)Institute of Chinese Materia Me... (China)Leibniz Institute of Plant Bioc... (Germany)Semmelweis Unicersity (Hungary)
University of Canterbury (New Zealand)Seoul National University (Korea)Research Unit Molecular Epigene... (Germany)
Related Screening Libraries
||Desmethylxanthohumol shows estrogenic activity.|
|Planta Medica, 2009, 75(07):757-762. |
|Dynamic Residual Complexity of Natural Products by qHNMR: Solution Stability of Desmethylxanthohumol.[Reference: WebLink]|
|The use of chromatographic assays to assess the residual complexity of materials that are purified from natural sources by chromatographic means is, in a sense, a case of the fox watching the henhouse. Beside their static residual complexity, which is intrinsic to their metabolic origin, biologically active natural materials can also be involved in chemical reactions that lead to dynamic residual complexity.
METHODS AND RESULTS:
The present study examines the dynamics of the hop prenylphenol, Desmethylxanthohumol (DMX), by means of quantitative ¹H-NMR (qHNMR) in a setting that mimics in vitro and physiological conditions. The experiments provide a comprehensive, time-resolved, and mechanistic picture of the spontaneous isomerization of DMX into congeneric flavanones, including their ¹H/²D isotopomers. Formation of the potent phytoestrogen, 8-prenylnaringenin (8PN), suggests that measurable estrogenic activity even of high-purity DMX is an artifact. Together with previously established qHNMR assays including purity activity relationships (PARs), dynamic qHNMR assays complement important steps of the post-isolation evaluation of natural products.
Thus, qHNMR allows assessment of several unexpected effects that potentially break the assumed linkage between a single chemical entity (SCE) and biological endpoints.
||The herbs of Humulus lupulus
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Journal of Agricultural and Food Chemistry, 2007, 55(1):61-66. |
|Relevance of organic farming and effect of climatological conditions on the formation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol in hop (Humulus lupulus L.).[Reference: WebLink]|
|The concentrations of alpha-acids, beta-acids, Desmethylxanthohumol, and xanthohumol were monitored in the hop varieties Admiral (A), Wye Challenger (WC), and First Gold (FG) during the harvest seasons of 2003 through 2005.
METHODS AND RESULTS:
Hops grown under an organic regimen were compared to plants grown conventionally in hop fields in close vicinity. The concentrations of the key compounds depended very much on climatological conditions showing, in general, highest levels in poorest weather conditions (2004). Of the three varieties studied, FG was the only one showing a clear trend for higher concentrations of secondary metabolites under organic growing conditions than under conventional farming conditions. Cultivation of A and WC seems to be very sensitive to climatic conditions and environmental stresses caused by pests and diseases, thereby leading to various results.
WC proved to be a rich source of bioactive chalcones, particularly Desmethylxanthohumol.