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    Eupalinilide D
    CAS No. 757202-14-5 Price $363 / 10mg
    Catalog No.CFN90380Purity>=98%
    Molecular Weight314.76Type of CompoundSesquiterpenoids
    FormulaC15H19ClO5Physical DescriptionCryst.
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)
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    Eupalinilide D Description
    Source: The herbs of Eupatorium lindleyanum DC.
    Biological Activity or Inhibitors:
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.177 mL 15.8851 mL 31.7702 mL 63.5405 mL 79.4256 mL
    5 mM 0.6354 mL 3.177 mL 6.354 mL 12.7081 mL 15.8851 mL
    10 mM 0.3177 mL 1.5885 mL 3.177 mL 6.354 mL 7.9426 mL
    50 mM 0.0635 mL 0.3177 mL 0.6354 mL 1.2708 mL 1.5885 mL
    100 mM 0.0318 mL 0.1589 mL 0.3177 mL 0.6354 mL 0.7943 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Eupalinilide D References Information
    Citation [1]

    J Nat Prod. 2004 Sep;67(9):1470-5.

    Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum.[Pubmed: 15387644]
    Ten new guaiane type sesquiterpene lactones, namely, Eupalinilide A(1), eupalinilide B (2), eupalinilide C (3), Eupalinilide D (4), eupalinilide E (5), eupalinilide F (6), and eupalinilide G(7), eupalinilide H (8), eupalinilide I (9), eupalinilide J (10), as well as nine known compounds, eupachinilide C (11), eupachifolin D (12), eupachinilide E (13), 2alpha-hydroxyeupatolide (14), 3-deacetyleupalinin A (15), heliangine (16), 8beta-tigloyloxy-2,3-seco-6betaH,7alphaH-helianga-4Z,11(13)-diene-3,10beta;6, 12-diolid-2-oic acid (17), 8beta-(4'-hydroxytigloyloxy)-3beta,14-dihydroxy-6betaH,7alphaH-germacra-1(10)Z,4Z,11(13)-trien-6,12-olide (18), and 8beta-tigloyloxy-3beta,14-dihydroxy-6betaH,7alphaH-germacra-1(10)Z,4E,11(13)-trien-6,12-olide (19), were isolated from the whole plant of Eupatorium lindleyanum. Eupalinilide B (2), eupalinilide C (3), eupalinilide E (5), eupalinilide F (6), and eupalinilide I (9) have been tested for cytotoxicity against P-388 and A-549 tumor cell lines. The results showed that eupalinilide B (2) and eupalinilide E (5) demonstrated potent cytotoxicity. The structures of these compounds were determined by spectroscopic methods including 1D and 2D NMR spectra.