Ganoderenic acid D | CAS:100665-43-8 | Product Use Citation

Ganoderenic acid D

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Ganoderenic acid D Description

Source:	The fruit body of Ganoderma lucidum
Biological Activity or Inhibitors:	1. Ganoderenic acid D is most cytotoxic with IC50 values of 0.14 ± 0.01, 0.18 ± 0.02 and 0.26 ± 0.03 mg/mL in Hep G2, Hela and Caco-2 cells, respectively.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.

PMID: 29328914

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.

PMID: 29149595

Scientific Reports 2017 Dec 11;7(1):17332.
doi: 10.1038/s41598-017-17427-6.

PMID: 29230013

Molecules. 2017 Oct 27;22(11). pii: E1829.
doi: 10.3390/molecules22111829.

PMID: 29077044

J Cell Biochem. 2018 Feb;119(2):2231-2239.
doi: 10.1002/jcb.26385.

PMID: 28857247

Phytomedicine. 2018 Feb 1;40:37-47.
doi:10.1016/j.phymed.2017.12.030

PMID: 29496173

Ganoderenic acid D References Information

Citation [1]

Natural Product Research, Volume 28, Number 24, 17 December 2014, pp. 2264-2272(9)

Extraction optimisation and isolation of triterpenoids from Ganoderma lucidum and their effect on human carcinoma cell growth[Reference: WebLink]

Following extraction, triterpenoid-enriched fraction was further isolated into 23 fractions, and 7 fractions were identified as ganoderic acids A, B, D, G, H and I and Ganoderenic acid D. Of the seven triterpenoids, Ganoderenic acid D was most cytotoxic with IC50 values of 0.14 ± 0.01, 0.18 ± 0.02 and 0.26 ± 0.03 mg/mL in Hep G2, Hela and Caco-2 cells, respectively. While ganoderic acids A, G and H were relatively non-cytotoxic. The variation of inhibitory effects for these triterpenoids was likely related to their chemical structures.

CAS No.	100665-43-8	Price	$476 / 10mg
Catalog No.	CFN90300	Purity	>=98%
Molecular Weight	512.64	Type of Compound	Triterpenoids
Formula	C₃₀H₄₀O₇	Physical Description	Powder
Download	Manual COA MSDS SDF	Similar structural	Comparison (Web)

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.9507 mL	9.7534 mL	19.5069 mL	39.0137 mL	48.7672 mL
5 mM	0.3901 mL	1.9507 mL	3.9014 mL	7.8027 mL	9.7534 mL
10 mM	0.1951 mL	0.9753 mL	1.9507 mL	3.9014 mL	4.8767 mL
50 mM	0.039 mL	0.1951 mL	0.3901 mL	0.7803 mL	0.9753 mL
100 mM	0.0195 mL	0.0975 mL	0.1951 mL	0.3901 mL	0.4877 mL

CFN90574	Lucidenic acid A	95311-94-7	458.59	C₂₇H₃₈O₆
CFN95020	Lucidenic acid D2	98665-16-8	514.6	C₂₉H₃₈O₈
CFN92995	Lucidenic acid C	95311-96-9	476.60	C₂₇H₄₀O₇
CFN92994	Lucidenic acid SP1	364622-33-3	460.60	C₂₇H₄₀O₆
CFN90829	20(21)-Dehydrolucidenic acid A	852936-69-7	456.6	C₂₇H₃₆O₆
CFN91025	Lucidone B	97653-93-5	400.51	C₂₄H₃₂O₅
CFN91014	20-Hydroxyganoderic acid G	400604-12-8	548.67	C₃₀H₄₄O₉
CFN90293	Ganoderic acid N	110241-19-5	530.65	C₃₀H₄₂O₈
CFN92236	Ganoderenic acid A	100665-40-5	514.7	C₃₀H₄₂O₇
CFN90300	Ganoderenic acid D	100665-43-8	512.64	C₃₀H₄₀O₇