ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
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More articles cited ChemFaces products.
Molecules. 2016 Oct 20Scientific Reports2015 August 26 Molecules 2016, 21(6)2016 Jun 22;21(6). Braz J Med Biol Res. 2016 Jul 4;49(7).Curr Eye Res.2018 Jan;
Molecules.2017 Oct 27;Br J Pharmacol.2018 Mar;J Ethnopharmacol. 2017 Jul 12;Arch Biochem Biophys. 2018 Jan 15;Naunyn Schmiedebergs Arch Pharmacol. 2017 Jul 21.
Biochem Biophys Res Commun. 2018 Jan 1;Front Plant Sci. 2017 May 8;ARPN Journal of Eng.& Applied Sci.4, Feb. 2016 Acta Physiologiae Plantarum.2014 10.
Our products had been exported to the following research institutions and universities, And still growing.
Leibniz-Institut für Pflanzenbi... (Germany)Tohoku University (Japan)University of Wollongong (Australia)Kyoto University (Japan)
CSIRO - Agriculture Flagship (Australia)Universidad de La Salle (Mexico)Calcutta University (India)Cancer Research Initatives Found... (Malaysia)
University of Wisconsin-Madison (USA)Worcester Polytechnic Institute (USA)Molecular Biology Institute of B... (Spain)
Ganoderenic acid D Description
||The fruit body of Ganoderma lucidum
|Biological Activity or Inhibitors:
||1. Ganoderenic acid D is most cytotoxic with IC50 values of 0.14 ± 0.01, 0.18 ± 0.02 and 0.26 ± 0.03 mg/mL in Hep G2, Hela and Caco-2 cells, respectively.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Ganoderenic acid D References Information
Natural Product Research, Volume 28, Number 24, 17 December 2014, pp. 2264-2272(9)
|Extraction optimisation and isolation of triterpenoids from Ganoderma lucidum and their effect on human carcinoma cell growth[Reference: WebLink]|
|Following extraction, triterpenoid-enriched fraction was further isolated into 23 fractions, and 7 fractions were identified as ganoderic acids A, B, D, G, H and I and Ganoderenic acid D. Of the seven triterpenoids, Ganoderenic acid D was most cytotoxic with IC50 values of 0.14 ± 0.01, 0.18 ± 0.02 and 0.26 ± 0.03 mg/mL in Hep G2, Hela and Caco-2 cells, respectively. While ganoderic acids A, G and H were relatively non-cytotoxic. The variation of inhibitory effects for these triterpenoids was likely related to their chemical structures.