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  • Ganoderenic acid D
    • Ganoderenic acid D
    Ganoderenic acid D
    Information
    CAS No. 100665-43-8 Price $476 / 10mg
    Catalog No.CFN90300Purity>=98%
    Molecular Weight512.64Type of CompoundTriterpenoids
    FormulaC30H40O7Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)
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    Ganoderenic acid D Description
    Source: The fruit body of Ganoderma lucidum
    Biological Activity or Inhibitors: 1. Ganoderenic acid D is most cytotoxic with IC50 values of 0.14 ± 0.01, 0.18 ± 0.02 and 0.26 ± 0.03 mg/mL in Hep G2, Hela and Caco-2 cells, respectively.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
    More...

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9507 mL 9.7534 mL 19.5069 mL 39.0137 mL 48.7672 mL
    5 mM 0.3901 mL 1.9507 mL 3.9014 mL 7.8027 mL 9.7534 mL
    10 mM 0.1951 mL 0.9753 mL 1.9507 mL 3.9014 mL 4.8767 mL
    50 mM 0.039 mL 0.1951 mL 0.3901 mL 0.7803 mL 0.9753 mL
    100 mM 0.0195 mL 0.0975 mL 0.1951 mL 0.3901 mL 0.4877 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Ganoderenic acid D References Information
    Citation [1]

    Natural Product Research, Volume 28, Number 24, 17 December 2014, pp. 2264-2272(9)

    		Extraction optimisation and isolation of triterpenoids from Ganoderma lucidum and their effect on human carcinoma cell growth[Reference: WebLink]
    Following extraction, triterpenoid-enriched fraction was further isolated into 23 fractions, and 7 fractions were identified as ganoderic acids A, B, D, G, H and I and Ganoderenic acid D. Of the seven triterpenoids, Ganoderenic acid D was most cytotoxic with IC50 values of 0.14 ± 0.01, 0.18 ± 0.02 and 0.26 ± 0.03 mg/mL in Hep G2, Hela and Caco-2 cells, respectively. While ganoderic acids A, G and H were relatively non-cytotoxic. The variation of inhibitory effects for these triterpenoids was likely related to their chemical structures.
    CFN90301Ganoderenic acid F120462-47-7510.63C30H38O7
    CFN90748Ganolactone B1028449-53-7458.6C27H38O6
    CFN90970Ganoderlactone D1801934-15-5474.26C27H38O7
    CFN90574Lucidenic acid A95311-94-7458.59C27H38O6
    CFN95020Lucidenic acid D298665-16-8514.6C29H38O8
    CFN92995Lucidenic acid C95311-96-9476.60C27H40O7
    CFN92994Lucidenic acid SP1364622-33-3460.60C27H40O6
    CFN9082920(21)-Dehydrolucidenic acid A852936-69-7456.6C27H36O6
    CFN91025Lucidone B97653-93-5400.51C24H32O5
    CFN9101420-Hydroxyganoderic acid G400604-12-8548.67C30H44O9
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