ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Biochem Systematics and EcologyOctober 2017;Oncol Rep.2015 Dec 22. Mol Cells.2015 Sep 30;38(9):765-72.Oncology LettersJan. 25, 2018;Molecules.2013 Nov 14;18(11):14105-21.
J Agric Food Chem. 2017 Apr 5J. Agric. Food Chem.,2015, 63 (44), 9869–9878FEMS Microbiol Lett. 2017 Jun 15;Phytother Res.2018 Jan 29.ARPN Journal of Eng.& Applied Sci.4, Feb. 2016
BMC Complement Altern Med.2017 Aug 9;Int J Mol Sci. 2018 Jan 23;The Japan Society for Analy. Chem.2017 Nov. 8;Sci Rep. 2016 Apr 27
Our products had been exported to the following research institutions and universities, And still growing.
Medizinische Universit?t Wien (Austria)University of Vigo (Spain)Subang Jaya Medical Centre (Malaysia)Universiti Kebangsaan Malaysia (Malaysia)
Seoul National University of Sci... (Korea)Ain Shams University (Egypt)Kamphaengphet Rajabhat University (Thailand)University of Medicine and Pharm... (Romania)
National Research Council of Can... (Canada)Uniwersytet Jagielloński w Krak... (Poland)University of Ioannina (Greece)
|| Hispidulin 7-O-neohesperidoside is one of the active substances responsible for the protective effects of this plant.|
|Phytother Res. 2004 Jan;18(1):19-24. |
|Effects of methanol extract of Cirsium japonicum var. ussuriense and its principle, hispidulin-7-O-neohesperidoside on hepatic alcohol-metabolizing enzymes and lipid peroxidation in ethanol-treated rats.[Pubmed: 14750195]|
|Effects of the methanol extract of Cirsium japonicum var. ussuriense and Hispidulin 7-O-neohesperidoside isolated from the plant on hepatic alcohol-metabolizing enzymes and lipid peroxidation were studied in rats treated with ethanol.
METHODS AND RESULTS:
Rats treated with 10% alcohol solution for 6 weeks were orally administered with 250 or 500 mg of methanol extract or 10 or 20 mg of Hispidulin 7-O-neohesperidoside per kg body weight daily during the last week of ethanol treatment. The administration of the methanol extract of herbal plant and Hispidulin 7-O-neohesperidoside in ethanol-treated rats significantly enhanced the activities of hepatic alcohol dehydrogenase, microsomal ethanol-oxidizing system and aldehyde dehydrogenase in a dose-dependent manner. The extract and the compound decreased hepatic lipid peroxidation along with an increase in hepatic content of reduced glutathione. The methanol extract and Hispidulin 7-O-neohesperidoside of C. japonicum var. ussuriense also increased the activity of glutathione reductase, but had no effect on gamma-glutamylcysteine synthase.
The results suggest that C. japonicum var. ussuriense may alleviate alcoholic toxicity by enhancing ethanol oxidation as well as inhibiting lipid peroxidation, and Hispidulin 7-O-neohesperidoside is one of the active substances responsible for the protective effects of this plant.
Hispidulin 7-O-neohesperidoside Description
||The herbs of Plantago asiatica L.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.