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  • (-)-Isodocarpin
    • (-)-Isodocarpin
    (-)-Isodocarpin
    Information
    CAS No. 10391-08-9 Price
    Catalog No.CFN92313Purity>=98%
    Molecular Weight346.4Type of CompoundDiterpenoids
    FormulaC20H26O5Physical DescriptionCryst.
    Download     COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
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    Description: Reference standards.
    (-)-Isodocarpin Description
    Source: The herbs of Isodon japonicus
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8868 mL 14.4342 mL 28.8684 mL 57.7367 mL 72.1709 mL
    5 mM 0.5774 mL 2.8868 mL 5.7737 mL 11.5473 mL 14.4342 mL
    10 mM 0.2887 mL 1.4434 mL 2.8868 mL 5.7737 mL 7.2171 mL
    50 mM 0.0577 mL 0.2887 mL 0.5774 mL 1.1547 mL 1.4434 mL
    100 mM 0.0289 mL 0.1443 mL 0.2887 mL 0.5774 mL 0.7217 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Angewandte Chemie International Edition.
    Divergent Total Syntheses of Enmein-Type Natural Products:(-)-Enmein, (-)-Isodocarpin and (-)-Sculponin R.[Reference: WebLink]

    METHODS AND RESULTS:
    Divergent total syntheses of enmein-type natural products, (–)-enmein, (-)-Isodocarpin and (–)-sculponin R, have been achieved in a concise fashion.
    CONCLUSIONS:
    Key features of the strategy include (a) an efficient early-stage cage formation to control succeeding diastereoselectivity, (b) an one-pot acylation/akylation/lactonization to construct the C-ring and C8 quarternary center, (c) a reductive alkenylation approach to construct enmain D/E rings and (d) a flexible route to allow divergent syntheses of three natural products.
    CFN92313(-)-Isodocarpin10391-08-9346.4C20H26O5
    CFN92435Enmein3776-39-4362.4C20H26O6
    CFN92315Epinodosin20086-60-6362.4C20H26O6
    CFN99056Nodosin10391-09-0362.4 C20H26O6
    CFN97414Sculponeatin A85287-60-1360.4 C20H24O6
    CFN96677Serrin A845959-98-0390.47C22H30O6
    CFN89366Carpalasionin83150-97-4420.45C22H28O8
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