• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Jionoside B1
    Information
    CAS No. 120406-37-3 Price $448 / 10mg
    Catalog No.CFN90729Purity>=98%
    Molecular Weight814.78Type of CompoundPolyphenols
    FormulaC37H50O20Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Chang Gung University (Taiwan)
  • University of Illinois (USA)
  • University of East Anglia (United Kingdom)
  • Charles Sturt University (Denmark)
  • Universite de Lille1 (France)
  • Florida International University (USA)
  • Seoul National University (Korea)
  • University of Melbourne (Australia)
  • University Medical Center Mainz (Germany)
  • Universiti Sains Malaysia (Malaysia)
  • Warszawski Uniwersytet Medyczny (Poland)
  • More...
  • Package
    Featured Products
    Gnetol

    Catalog No: CFN92425
    CAS No: 86361-55-9
    Price: $388/5mg
    Kaempferol 3-O-arabinoside

    Catalog No: CFN97572
    CAS No: 99882-10-7
    Price: $398/5mg
    Acetylshikonin

    Catalog No: CFN90308
    CAS No: 54984-93-9
    Price: $418/20mg
    Platycodigenin

    Catalog No: CFN92207
    CAS No: 22327-82-8
    Price: $338/10mg
    Kawain

    Catalog No: CFN92656
    CAS No: 500-64-1
    Price: $158/20mg
    Biological Activity
    Description: Jionoside B1 has immunosuppressive activity, it shows the hepato-protective activity in the H2O2 induced liver injury experiments.Jionoside B1 exhibits the obvious inhibition against aldose reductase.
    In vitro:
    Chinese Traditional & Herbal Drugs, 2016, 47(11): 1830-3.
    Chemical constituents from whole plants of oehmannia chingii[Reference: WebLink]
    To investigate the chemical constituents of Rehmannia chingii.
    METHODS AND RESULTS:
    The compounds were isolated from an aqueous extract from the whole plants of R.chingii by a combination of various chromatographic techniques including column chromatography over silica gel and Sephadex LH-20 and reversed-phase HPLC.Their structures were identified by spectroscopic analysis including MS and NMR data. Seventeen compounds were isolated and identified as 8-methyloctahydrocyclopenta [c] pyran-1,3,6,8-tetraol(1),3,4-dihydroxy-phenethyl alcohol(2),3-methoxyl-4-hydroxyphenyl alcohol(3),phenylethyl-8-O-β-D-glucopyranoside(4),3,4-dihydroxy-β-phenethyl-O-α-L-rhamnopyranosyl-(1→3)-O-β-D-glucopyranoside(5),2-phenylethylO-β-D-xylopyranosyl-(1→6)-β-D-glucopyranoside(6),deacyl-martynoside(7),acteoside(8),isoacteoside(9),martynoside(10),isomartynoside(11),jionoside C(12),jionoside A1(13),Jionoside B1(14),3,4-dihydroxy-β-phenethyl-O-α-L-rhamnopyranosyl-(1→3)-O-β-D-galacopyranosyl-(1→6)-4-O-caffeoyl-β-D-glucopyranoside(15),cistanoside F(16),and isocistanoside F(17).
    CONCLUSIONS:
    Among the isolated seventeen compounds,compound 1 is a new compound named rehmachinin,and compounds 16-17 are isolated from the plants of Rehmannia Libosch.ex Fisch.et Mey.for the first time. In the preliminary assays,compounds 9,12,and 14-16 exhibit the obvious inhibition against aldose reductase.
    Jionoside B1 Description
    Source: The roots of Rehmannia glutinosa
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    1-Methoxycarbonyl-beta-carboline-N...

    Catalog No: CFN95023
    CAS No: 74690-74-7
    Price: $413/5mg
    Skullcapflavone II

    Catalog No: CFN92216
    CAS No: 55084-08-7
    Price: $318/10mg
    2-Cinnamoyl-1-galloylglucose

    Catalog No: CFN95098
    CAS No: 56994-83-3
    Price: $338/5mg
    Ampelopsin F

    Catalog No: CFN92340
    CAS No: 151487-08-0
    Price: $413/5mg
    Morusinol

    Catalog No: CFN97086
    CAS No: 62949-93-3
    Price: $388/5mg
    Arjunglucoside I

    Catalog No: CFN95049
    CAS No: 62319-70-4
    Price: $268/10mg
    1,3,6-Tri-O-galloylglucose

    Catalog No: CFN95043
    CAS No: 18483-17-5
    Price: $338/10mg
    Bisabolangelone

    Catalog No: CFN91876
    CAS No: 30557-81-4
    Price: $413/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.2273 mL 6.1366 mL 12.2733 mL 24.5465 mL 30.6831 mL
    5 mM 0.2455 mL 1.2273 mL 2.4547 mL 4.9093 mL 6.1366 mL
    10 mM 0.1227 mL 0.6137 mL 1.2273 mL 2.4547 mL 3.0683 mL
    50 mM 0.0245 mL 0.1227 mL 0.2455 mL 0.4909 mL 0.6137 mL
    100 mM 0.0123 mL 0.0614 mL 0.1227 mL 0.2455 mL 0.3068 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Zhongguo Zhong Yao Za Zhi. 2011 Nov;36(22):3125-9.
    Chemical constituents from Rehmannia glutinosa.[Pubmed: 22375391]
    To study the chemical constituents from the roots of Rehmannia glutinosa.
    METHODS AND RESULTS:
    The compounds were isolated by various chromatographic methods and identified by spectroscopic analysis. Twelve compounds were isolated and their structures were identified as 5-hydroxymethyl-pyrrole-2-carbaldehyde (1), 5-hydroxymethyl furfural (2), tyrosol (3), 5,6-dihydroxy-beta-ionone (4), 6-O-E-feruloyl ajugol (5), acteoside (6), leucosceptoside A (7), martynoside (8), isomartynoside (9), purpureaside C (10), jionoside A1 (11), and Jionoside B1 (12).
    CONCLUSIONS:
    Compounds 1, 3 and 9 were isolated from the genus Rehmannia for the first time.