Lauterine | CAS:28200-65-9 | Manufacturer ChemFaces

Lauterine

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Continentalic acid

Catalog No: CFN90861
CAS No: 19889-23-7
Price: $168/20mg

Juglone

Catalog No: CFN90497
CAS No: 481-39-0
Price: $40/20mg

Ginsenoside Rh4

Catalog No: CFN92594
CAS No: 174721-08-5
Price: $368/10mg

Chrysin

Catalog No: CFN98741
CAS No: 480-40-0
Price: $40/20mg

Honokiol

Catalog No: CFN99902
CAS No: 35354-74-6
Price: $30/20mg

Demethylzeylasteral

Catalog No: CFN90136
CAS No: 107316-88-1
Price: $40/20mg

Vitexin

Catalog No: CFN98601
CAS No: 3681-93-4
Price: $60/20mg

Corynantheine

Catalog No: CFN92843
CAS No: 18904-54-6
Price: $ / mg

3-Epidehydropachymic acid

Catalog No: CFN92738
CAS No: 168293-15-0
Price: $318/5mg

Complanatoside B

Catalog No: CFN80156
CAS No: 142473-99-2
Price: $218/10mg

Description:

Lauterine is a DNA topoisomerase inhibitor.

Targets:

Topoisomerase

In vitro:

J Nat Prod. 1994 Jan;57(1):68-73.

Isolation of bioactive and other oxoaporphine alkaloids from two annonaceous plants, Xylopia aethiopica and Miliusa cf. banacea.[Pubmed: 8158166]

METHODS AND RESULTS:
The oxoaporphine alkaloids oxophoebine [1] and liriodenine [2] have been isolated from Xylopia aethiopica (Annonaceae). Both showed selective toxicity against DNA repair and recombination deficient mutants of the yeast Saccharomyces cerevisae. Three related but inactive compounds, oxoglaucine [3], O-methylmoschatoline [4], and lysicamine [5], were also isolated from this plant. Selective toxicity was also observed for 10-methoxyliriodenine (Lauterine) [6] and 10-hydroxyliriodenine [7], two oxoaporphine alkaloids isolated from Miliusa cf. banacea (Annonaceae). The structure of 10-hydroxyliriodenine [7], a novel oxoaporphine, was determined by spectroscopic methods and chemical conversion to compound 6.
CONCLUSIONS:
The role of the bioactive oxoaporphine alkaloids as DNA topoisomerase inhibitors is discussed.

Lauterine Description

Source:	The plants of Guatteria elata R. E. Fries.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Lauterine
Price:
CAS No.:	28200-65-9
Catalog No.:	CFN96757
Molecular Formula:	C₁₈H₁₁NO₄
Molecular Weight:	305.28 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The plants of Guatteria elata R. E. Fries.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Alkaloids Compound Library Topoisomerase Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.2757 mL	16.3784 mL	32.7568 mL	65.5136 mL	81.892 mL
5 mM	0.6551 mL	3.2757 mL	6.5514 mL	13.1027 mL	16.3784 mL
10 mM	0.3276 mL	1.6378 mL	3.2757 mL	6.5514 mL	8.1892 mL
50 mM	0.0655 mL	0.3276 mL	0.6551 mL	1.3103 mL	1.6378 mL
100 mM	0.0328 mL	0.1638 mL	0.3276 mL	0.6551 mL	0.8189 mL

CFN89485	6-Formyl-1,2,9,10-tetramethoxy-6a,7-dehydroaporphine	2101836-45-5	367.39	C₂₁H₂₁NO₅
CFN97889	Cassyfiline	4030-51-7	341.4	C₁₉H₁₉NO₅
CFN96039	1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine	14050-90-9	355.4	C₂₀H₂₁NO₅
CFN97932	Aporheine	2030-53-7	279.3	C₁₈H₁₇NO₂
CFN97947	Neolitsine	2466-42-4	323.4	C₁₉H₁₇NO₄
CFN90508	Oxoglaucine	5574-24-3	351.34	C₂₀H₁₇NO₅
CFN98715	Liriodenine	475-75-2	275.3	C₁₇H₉NO₃
CFN96757	Lauterine	28200-65-9	305.28	C₁₈H₁₁NO₄
CFN93254	Lysicamine	15444-20-9	291.3	C₁₈H₁₃NO₃
CFN89535	3-Methoxyoxohernandaline	872729-34-5	531.51	C₂₉H₂₅NO₉