ChemFaces is a professional high-purity natural products manufacturer.
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $222.6 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Korean Journal of Pharmacognosy...2014...Phytomedicine.2015, 22(11):1027-36Am J Chin Med.2015, 30:1-22Inflammation2015, 38(1):445-55Research on Crops.2017, 18(2)Int J Anal Chem.2017, 2017:1254721Universite de Bordeaux...2017...Korean J of Food Science&Technolo...2017...
LWT-Food Science and Technology...2017...Viruses.2017, 9(10)Oncotarget.2017, 9(3):4161-4172Korean J of Medicinal Crop Scienc...2018...Molecules.2018, 23(10):E2638Front Cell Infect Microbiol.2018, 8:292Front Plant Sci.2018, 9:1424Molecules.2019, 24(1):E159
Exp Biol Med (Maywood)....2019...Environ Toxicol.2019, 34(12):1354-1362Journal of Third Military Medical...2019...Int Immunopharmacol.2019, 71:361-371Metabolites.2019, 9(11):E271Biomedicine & Pharmacotherapy...2020...Antioxidants (Basel).2020, 9(2):E99
Our products had been exported to the following research institutions and universities, And still growing.
Universiti Malaysia Pahang (Malaysia)Universitas islam negeri Jakarta (Indonesia)University of Wisconsin-Madison (USA)University of Perugia (Italy)
National Cancer Center Research... (Japan)University of Queensland (Australia)Mahidol University (Thailand)The Australian National University (Australia)
Centralised Purchases Unit (CPU... (India)University of Pretoria (South Africa)Florida International University (USA)
Related Screening Libraries
||Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.|
|Bioorg Med Chem. 2009 Sep 1;17(17):6251-6. |
|Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines.[Pubmed: 19664930 ]|
METHODS AND RESULTS:
A series of analogs were synthesized in a straightforward manner from naturally available sesquiterpenes ilicic acid and Tessaric acid. The in vitro antiproliferative activities were examined in the human solid tumor cell lines A2780, HBL-100, HeLa, SW1573, T-47D and WiDr. The most potent analog induced considerably growth inhibition in the range 1.9-4.5 microM.
Cell cycle studies for Tessaric acid derivatives indicated a prominent arrest of the cell cycle at the G(2)/M phase. Damage to the cells was permanent as determine by the so called 24+24 drug schedule.
|Z Naturforsch C. 2005 Nov-Dec;60(11-12):855-61. |
|Antifeedant/insecticidal terpenes from asteraceae and labiatae species native to Argentinean semi-arid lands.[Pubmed: 16402545 ]|
|To validate the potential as added-value resources of Asteraceae and Labiatae species of Argentinean semi-arid lands, we have selected 13 of their major terpenoids belonging to several chemical classes and tested their insect antifeedant and toxic activity on the herbivorous insects Spodoptera littoralis and Leptinotarsa decemlineata.
METHODS AND RESULTS:
The antifeedant effects of the test compounds were structure- and species-dependent. The most active antifeedant to L. decemlineata was the eudesmane sesquiterpene gamma-costic acid (13), followed by the labdane diterpene 2alpha,3alpha-dihydroxycativic acid (8), the clerodane diterpenes 6-acetylteucjaponin B (5), bacchotricuneatin A (1), bartemidiolide (7), butanolide (4), and the sesquiterpenes ilicic acid (11) and Tessaric acid (10) (eudesmane and eremophilane type, respectively). S. littoralis was only affected by the clerodanes and showed the strongest response to salviarin (3) and 5, followed by hawtriwaic acid (6) and 12-epi-bacchotricuneatin A (2).
Orally injected S. littoralis larvae were negatively affected by 5. Most of the diterpenes had selective cytotoxic effects to insect-derived Sf9 cells with the clerodane 1 being the most active, followed by the eudesmane costic acid (12), the only cytotoxic sesquiterpene. None of these compounds was cytotoxic to mammalian CHO cells.
|J Chem Ecol. 2003 Jan;29(1):175-87. |
|Allelochemical effects of eudesmane and eremophilane sesquiterpenes on Tribolium castaneum larvae.[Pubmed: 12647861]|
METHODS AND RESULTS:
Eight eudesmane and eremophilane sesquiterpenes administered to Tribolium castaneum larvae caused different allelochemical effects. Topical application of 3-oxo-gamma-costic acid produced the greatest lengthening in the duration of the pupal stage. Morphological deformities were found, specifically when ilicic, costic, and gamma-costic acids and costic aldehyde were used. Ilicic acid exhibited the major toxicity 72 hr following topical application. All compounds were significantly toxic at the end point of the experiment (60 days). Treated surface toxicity was lower than when topical assays were carried out.
Responses to Tessaric acid in choice bioassays had the highest attractive effect. Maximum repellency was caused by the 3-oxo-gamma-costic acid. However, experimental series carried out using gamma-costic acid, eremophilan-1(10),2,11(13)-trien-12-oic acid, costic aldehyde, and ilicic aldehyde showed no clear response.
Tessaric acid Description
||The herbs of Tessaria absinthioides
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.