ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
Scientific ResearchJune 20, 2017Evid Based Complement Alternat Med. 2017:6360836.Int J Mol Sci.2015 Aug 7;16(8):18396-411.?Pharmacogn Mag.2015 Jul-Sep.Chem Biol Interact.2018 Mar 1;
Evid Based Complement Alternat Med. 2016 May 24; Institute of Materia Medica2016 Mar 31, pp.29-35Mol Med Rep.2014 May;9(5):1653-9.J Pharm Biomed Anal.2018 Mar 20;J Agric Food Chem.2018 Jan 10;
Proc Natl Acad Sci U S A. 2016 Jul 26;Int J Oncol. 2016 Oct;49(4)Inflammation. 2015 Feb 6.Food and Bioprocess TechnologyJune 2017
Our products had been exported to the following research institutions and universities, And still growing.
Monash University Malaysia (Malaysia)University of Cincinnati (USA)University of Indonesia (Indonesia)National Hellenic Research Found... (Greece)
Shanghai Institute of Organic Ch... (China)University of Lodz (Poland)Universidade Federal de Goias (U... (Brazil)Stanford University (USA)
Korea Institute of Oriental Medi... (Korea)Colorado State University (USA)Chulalongkorn University (Thailand)
||Traditional formula compatibility of Danggui-Shaoyao-San could significantly enhance levistilide A bioavailability compared with levistilide A alone and Rhizoma Chuanxiong.|
Levistilide A Description
||The roots of Angelica sinensis
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi: 10.1016/j.phymed.2017.12.030.PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Chromatogr Sci. 2015 Feb 5. pii: bmu224. |
|Study on Pharmacokinetics of Three Preparations from Levistolide A by LC-MS-MS.[Pubmed: 25657289]|
|A rapid sensitive analytical method was established and validated to investigate levistolide A in rat plasma by liquid chromatography-tandem mass spectrometry operated in the positive ion mode.
METHODS AND RESULTS:
Levistilide A (LA) and internal standard (IS) andrographolide (AD), mixed with the plasma sample, were separated on a reversed phase Spursil™ C18 5 μm column. The precursor/product transitions (m/z) were 398.5/381.3 for Levistilide A and (m/z) 368.0/351.1 for AD. The calibration curve was linear over the range from 5 to 1,250 ng/mL for oral administration and 10-4,000 for intravenous administration with a correlation coefficient (r) ≥0.9993. The lower limit of quantification was 5 ng/mL for Levistilide A in plasma. The inter- and intra-day accuracy and precision were less than ±15% of the relative standard deviation. In this study, the developed method is successfully applied to the comparative pharmacokinetic study of Levistilide A in rats after oral administration of Levistilide A alone, Rhizoma Chuanxiong, and Danggui-Shaoyao-San along with the bioavailability study of Levistilide A in rats.
Our study shows that low bioavailability (7.5%) is observed after oral administration of Levistilide A .Traditional formula compatibility of Danggui-Shaoyao-San could significantly enhance Levistilide A bioavailability compared with Levistilide A alone and Rhizoma Chuanxiong.