ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Journal of Medicinal Plant Research.2013 Nov 7J Sep Sci.2018 Jan 23.Molecules 2016, 21(6)2016 Jun 22;21(6). Molecules. 2018 Jan 24;Arch Pharm Res.2014 Oct 18.
J Cell Biochem.2018 Feb;Int J Mol Sci. 2017 May 11;Int. J. of Food Properties08 Feb 2017;Journal of Life Science2017.2;British Jou. Med. & Med. Research2014 Jan 1
Tropical J. of Pha. ResearchNo 3 (2017) Horticultural Science2016Biochem Pharmacol. 2017 Apr 15;Molecules. 2017 Feb 8;
Our products had been exported to the following research institutions and universities, And still growing.
Michigan State University (USA)Monash University (Australia)Research Unit Molecular Epigenet... (Germany)Uniwersytet Gdański (Poland)
University of Queensland (Australia)Worcester Polytechnic Institute (USA)Universidade de Franca (Brazil)Chinese University of Hong Kong (China)
University of Brasilia (Brazil)The University of Newcastle (Australia)University of Liège (Belgium)
||1. Longiferone B shows anti-inflammatory activity against NO release with IC50 values of 21.0 uM, it also suppresses the iNOS and COX-2 mRNA expression. |
||NO | NOS | COX|
Longiferone B Description
||The rhizomes of Boesenbergia longiflora (Wall.) Kuntze.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi: 10.1016/j.phymed.2017.12.030.PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Longiferone B References Information
J Ethnopharmacol. 2014 Jun 11;154(2):453-61
|Anti-inflammatory activity of compounds from Boesenbergia longiflora rhizomes.[Pubmed: 24786574 ]|
|The isolation of the CHCl3 fraction from Boesenbergia longiflora rhizomes led to the isolation of three new daucane sesquiterpenes, which were identified as 8-hydroxy-dauca-9, 11-diene-7-one (longiferone A; 1), dauca-8, 11-diene-7-one (Longiferone B; 2) and dauca-8, 11-diene-7, 10-dione (longiferone C; 3); together with four known flavonoids, six known diarylheptanoids as well as one sterol. The Longiferone B (2) and longiferone C (3) showed anti-inflammatory activity against NO release with IC50 values of 21.0 and 31.3μM, respectively. Longiferone B (2) also suppressed the iNOS and COX-2 mRNA expression. Moreover, the flavonoids and diarylheptanoids inhibited NO and TNF-α production in a dose dependent manner.
This study demonstrated that sesquiterpenes, diarylheptanoids and some methoxyflavonoids found in Boesenbergia longiflora are responsible for anti-inflammatory activity.