ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Int J Mol Sci. 2014, 15(5):8443-57Korean Journal of Pharmacognosy....2015...Appl Microbiol Biotechnol....2016...Naunyn Schmiedebergs Arch Pharmac...2017...Nutrients.2018, 11(1):E17Sci Rep. 2018, 1-9Evid Based Complement Alternat Me...2018...Biochem Biophys Res Commun....2018...
Biochem Biophys Res Commun....2018...Pathogens.2018, 7(3):E62Int J Mol Sci.2019, 20(3):E651J Ethnopharmacol.2019, 228:132-141Molecules.2019, 24(16):E2985J Ethnopharmacol.2019, 241:112025Food Chem.2019, 274:345-350FASEB J.2019, 33(8):9685-9694
Kor. J. Herbol.2019, 34(2):59-66Journal of Food Hygiene and Safet...2019...Chin J Appl. Physiol....2019...The Malaysian journal of patholog...2019...Phytomedicine.2019, 67:153159Comput Biol Chem.2019, 83:107096Planta Med.2019, 85(9-10):766-773
Our products had been exported to the following research institutions and universities, And still growing.
Institute of Bioorganic Chemist... (Poland)Copenhagen University (Denmark)University of Helsinki (Finland)University of Illinois (USA)
Chiang Mai University (Thailand)University of Virginia (USA)Washington State University (USA)Seoul National University of Sc... (Korea)
University of Amsterdam (Netherlands)National Cancer Institute (USA)Utrecht University (Netherlands)
Related Screening Libraries
|| Longiferone B shows anti-inflammatory activity against NO release with IC50 values of 21.0 uM, it also suppresses the iNOS and COX-2 mRNA expression. |
||NO | NOS | COX|
|J Ethnopharmacol. 2014 Jun 11;154(2):453-61 |
|Anti-inflammatory activity of compounds from Boesenbergia longiflora rhizomes.[Pubmed: 24786574 ]|
METHODS AND RESULTS:
The isolation of the CHCl3 fraction from Boesenbergia longiflora rhizomes led to the isolation of three new daucane sesquiterpenes, which were identified as 8-hydroxy-dauca-9, 11-diene-7-one (longiferone A; 1), dauca-8, 11-diene-7-one (Longiferone B; 2) and dauca-8, 11-diene-7, 10-dione (longiferone C; 3); together with four known flavonoids, six known diarylheptanoids as well as one sterol. The Longiferone B (2) and longiferone C (3) showed anti-inflammatory activity against NO release with IC50 values of 21.0 and 31.3μM, respectively. Longiferone B (2) also suppressed the iNOS and COX-2 mRNA expression. Moreover, the flavonoids and diarylheptanoids inhibited NO and TNF-α production in a dose dependent manner.
This study demonstrated that sesquiterpenes, diarylheptanoids and some methoxyflavonoids found in Boesenbergia longiflora are responsible for anti-inflammatory activity.
Longiferone B Description
||The rhizomes of Boesenbergia longiflora (Wall.) Kuntze.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.