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    Lumichrome
    Lumichrome
    Information
    CAS No. 1086-80-2 Price
    Catalog No.CFN96780Purity>=98%
    Molecular Weight242.23Type of CompoundAlkaloids
    FormulaC12H10N4O2Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • The Vancouver Prostate Centre (... (Canada)
  • Center for protein Engineering ... (Belgium)
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    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Photosensitizer Compound Library
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  • Biological Activity
    Description: Lumichrome is a derivative of Riboflavin, a vitamin with a key role in maintaining cellular function and health in human and animals. Lumichrome shows photosensitizing effects on the generation of volatiles in soy milk.
    In vitro:
    J Agric Food Chem. 2006 Mar 22;54(6):2359-64.
    Photosensitizing effect of riboflavin, lumiflavin, and lumichrome on the generation of volatiles in soy milk.[Pubmed: 16536619]

    METHODS AND RESULTS:
    Lumichrome and lumiflavin were formed from riboflavin under light. pH had a significant influence on the formation of Lumichrome and lumiflavin from riboflavin. Lumichrome was the only major product from riboflavin under neutral or acidic pH values. Lumiflavin was also formed from riboflavin in basic pH. The maximum concentration of lumiflavin from 100 microM riboflavin at pH 8.5 was 30.9 microM, and it was reached after 2 h of exposure at 1500 lux. The maximum concentration of Lumichrome formed from 100 microM riboflavin at pH 4.5, 6.5, or 8.5 was 79.9, 58.7, and 73.1 microM, respectively, after 8, 6, or 2 h of light exposure. The formation of Lumichrome and lumiflavin from riboflavin was due to the type I mechanism of the riboflavin photosensitized reaction. Singlet oxygen was also involved in the photosensitized degradation of lumiflavin and Lumichrome. The reaction rates of riboflavin, lumiflavin, and Lumichrome with singlet oxygen were 9.66 x 10(8), 8.58 x 10(8), and 8.21 x 10(8) M(-1) s(-1), respectively. The headspace oxygen depletion and headspace volatile formation were significant in soy milk containing Lumichrome or lumiflavin under light (p < 0.05) and were insignificant (p > 0.05) in the dark.
    CONCLUSIONS:
    Ascorbic acid could inhibit the total volatile changes of soy milk under light. Soy milk should be protected from light to prevent the photodegradation of riboflavin and the oxidation of soy milk.
    Lumichrome Description
    Source: The aerial parts of Isodon excisoides.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.1283 mL 20.6415 mL 41.2831 mL 82.5662 mL 103.2077 mL
    5 mM 0.8257 mL 4.1283 mL 8.2566 mL 16.5132 mL 20.6415 mL
    10 mM 0.4128 mL 2.0642 mL 4.1283 mL 8.2566 mL 10.3208 mL
    50 mM 0.0826 mL 0.4128 mL 0.8257 mL 1.6513 mL 2.0642 mL
    100 mM 0.0413 mL 0.2064 mL 0.4128 mL 0.8257 mL 1.0321 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Zhongguo Zhong Yao Za Zhi. 2016 Sep;41(18):3361-3365.
    Studies on chemical constituents of Isodon excisoides.[Pubmed: 28925118]

    METHODS AND RESULTS:
    The chemical constituents of the water extraction of the aerial parts of Isodon excisoides were investigated by various chromatographic methods including D-101 macroporous adsorptive resins, silica gel, Sephadex LH-20, MCI and semi-preparative HPLC. As a result, six compounds were separated and purified.By analyses of the HR-ESI-MS, 1D and 2D NMR spectra, their structures were determined as 3-O-β-D-allopyranosyl-1-octen-3-ol(1), blumenolA (2), Lumichrome (3), loliolide(4), cirsiliol(5) and pedalitin(6).
    CONCLUSIONS:
    Compound 1 was a new compound, and compounds 2-4 were isolated from this plant for the first time.