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    Natural Products
    Oroxylin A 7-O-beta-D-glucuronide methyl ester
    Oroxylin A 7-O-beta-D-glucuronide methyl ester
    Information
    CAS No. 82475-01-2 Price
    Catalog No.CFN92282Purity>=98%
    Molecular Weight474.4Type of CompoundFlavonoids
    FormulaC23H22O11Physical DescriptionYellow powder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Description: Oroxylin A 7-O-beta-D-glucuronide methyl ester possibly possesses the potential immune activities.
    In vitro:
    Chinese Traditional and Herbal Drugs,2006.
    Study on flavonoids from Nicandra physaloides and their immune activities.[Reference: WebLink]
    To investigate the flavonoids from the fruits of Nicandra physaloides and clarify the immune activities of the isolated compounds.
    METHODS AND RESULTS:
    The separations and purifications were taken by silica gel and ODS chromatogram columns as well as preparative HPLC, and the structural identification based on physicochemical property, ¹H-NMR, and ¹³C-NMR as well as HR-MS data. And the immune activities were evaluated by mice splenic lymphocyte proliferation model induced by LPS. Thirteen compounds were obtained from the butanol fraction of the 70% ethanol extract of N. physaloides fruits, which were identified as 3''-hydroxy-puerarin (1), puerarin-6″-O-glucoside (2), daidzein 8-C-[α-D-apiofranosyl-(1→6)]-β-D-glucopyranoside (3), puerarin (4), 3''-methoxyl-puerarin (5), chrysin 6-C-α-L-arabinopyranosyl-8-C-β-D-glucopyranoside (6), Oroxylin A 7-O-beta-D-glucuronide methyl ester (7), daidzin (8), baicalin (9), quercetin-3-O-β-D-galactopyranoside (10), quercetin 3-rutinoside (11), kaempferol 3-rutinoside (12), and quercetin 3-glucoside (13), respectively. The results indicated that compounds 1-3, 7, 9-10, and 12-13 could inhibit the proliferation of mice spleen lymphocytes and 6 could promote the proliferation in the influence of mice spleen lymphocytes proliferation induced by LPS.
    CONCLUSIONS:
    Compounds 1-7 are isolated from the plants of Solanaceae for the first time, compounds 8-13 are obtained from the plants of Nicandra Adans. firstly. And the compounds 1-3, 6, 7, 9-10, and 12-13 possibly possess the potential immune activities.
    Oroxylin A 7-O-beta-D-glucuronide methyl ester Description
    Source: The roots of Scutellaria regeliana Nakai
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1079 mL 10.5396 mL 21.0793 mL 42.1585 mL 52.6981 mL
    5 mM 0.4216 mL 2.1079 mL 4.2159 mL 8.4317 mL 10.5396 mL
    10 mM 0.2108 mL 1.054 mL 2.1079 mL 4.2159 mL 5.2698 mL
    50 mM 0.0422 mL 0.2108 mL 0.4216 mL 0.8432 mL 1.054 mL
    100 mM 0.0211 mL 0.1054 mL 0.2108 mL 0.4216 mL 0.527 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.