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    Paniculidine B
    Information
    CAS No. 97399-94-5 Price
    Catalog No.CFN97553Purity>=98%
    Molecular Weight233.3 Type of CompoundAlkaloids
    FormulaC14H19NO2Physical DescriptionOil
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Description: Standard reference
    Paniculidine B Description
    Source: The herbs of Murraya exotica L.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

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    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
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    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.2863 mL 21.4316 mL 42.8633 mL 85.7265 mL 107.1582 mL
    5 mM 0.8573 mL 4.2863 mL 8.5727 mL 17.1453 mL 21.4316 mL
    10 mM 0.4286 mL 2.1432 mL 4.2863 mL 8.5727 mL 10.7158 mL
    50 mM 0.0857 mL 0.4286 mL 0.8573 mL 1.7145 mL 2.1432 mL
    100 mM 0.0429 mL 0.2143 mL 0.4286 mL 0.8573 mL 1.0716 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Org Chem. 2004 Jun 25;69(13):4429-32.
    Efficient total syntheses of phytoalexin and (+/-)-paniculidine B and C based on the novel methodology for the preparation of 1-methoxyindoles.[Pubmed: 15202897]

    METHODS AND RESULTS:
    A general route to 2-unsubstituted-1-methoxyindoles, based on our methodology for the synthesis of 1-methoxyindoles, is reported. This synthesis renders accessibility to a variety of natural products possessing the said skeleton. A direct synthesis of phytoalexin (1), (+/-)-Paniculidine B (2), and (+/-)-paniculidine C (3) is disclosed based on the methodology.
    CONCLUSIONS:
    The synthesis of Paniculidine B (2) has been achieved from aldehyde 10 in only two steps in 88% yield and in five steps from a methoxyindole compound 8 obtained using our earlier methodology.
    Chemical & Pharmaceutical Bulletin , 1985 , 33 (4) :1770-3
    Structures of paniculidines A and B: novel prenylindoles from Murraya paniculata[Reference: WebLink]

    METHODS AND RESULTS:
    Two new indoles named Paniculidine A and Paniculidine B were isolated from Murraya paniculata (Linn.) Jack., and their structures have been elucidated as methyl 2-methyl-4-(indol-3-yl)-butyrate and 2-methyl-4-(1-methoxyindol-3-yl)-1-butanol, respectively.