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    Parvifolixanthone A
    Parvifolixanthone A
    Information
    CAS No. 906794-56-7 Price
    Catalog No.CFN89058Purity>=98%
    Molecular Weight464.55Type of CompoundXanthones
    FormulaC28H32O6Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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  • Biological Activity
    Description: Parvifolixanthone A is a natural product from Garcinia parvifolia.
    In vitro:
    Chinese Traditional & Herbal Drugs, 2012, 43(3):436-439.
    Chemical constituents from stem barks of Garcinia paucinervis.[Reference: WebLink]
    To study the chemical constituents from the stem barks of Garcinia paucinervis and their antitumor activities.
    METHODS AND RESULTS:
    Chemical constituents were isolated and purified from petroleum ether extract of G.paucinervis by chromatography on silica gel,RP-18,Sephadex LH-20 column,and preparative TLC.Their structures were identified on the basis of spectroscopic analysis and chemical evidence.The antitumor activity was screened by MTT assay. Ten compounds were isolated and identified as cambogin(1),pyromeconic acid(2),β-sitosterol(3),daucosterol(4),7-prenyljacareubin(5),Parvifolixanthone A(6),formoxanthone A(7),termicalcicolanone A(8),1,3,5,6-tetrahydroxy-4-prenylxanthone(9),and isogarcinol(10).Compounds 5 and 7 showed moderate cytotoxic activity against HL-60,SMMC-7721,A549,MCF-7,and SW480 cell lines.
    CONCLUSIONS:
    Compounds 2—5 and 7—10 are isolated from this plant for the first time and the13C-NMR spectroscopic data of compound 5 are firstly reported.
    Parvifolixanthone A Description
    Source: The twigs of Garcinia parvifolia.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1526 mL 10.7631 mL 21.5262 mL 43.0524 mL 53.8155 mL
    5 mM 0.4305 mL 2.1526 mL 4.3052 mL 8.6105 mL 10.7631 mL
    10 mM 0.2153 mL 1.0763 mL 2.1526 mL 4.3052 mL 5.3816 mL
    50 mM 0.0431 mL 0.2153 mL 0.4305 mL 0.861 mL 1.0763 mL
    100 mM 0.0215 mL 0.1076 mL 0.2153 mL 0.4305 mL 0.5382 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Tetrahedron, 2006, 62(36):8578-8585.
    Phloroglucinols, depsidones and xanthones from the twigs of Garcinia parvifolia.[Reference: WebLink]

    METHODS AND RESULTS:
    Seven phloroglucinols, named parvifoliols A–G (1–7), two depsidones, named parvifolidones A, B (8, 9), and three xanthones, named Parvifolixanthone A, parvifolixanthone B, parvifolixanthone C (10–12), were isolated from the twigs of Garcinia parvifolia along with seven known compounds: garcidepsidone B, mangostinone, rubraxanthone, dulxanthone D, 1,3,5,6-tetrahydroxyxanthone, norathyriol, and (2E,6E,10E)-( )-4β-hydroxy-3-methyl-5β-(3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl)cyclohex-2-en-1-one.
    CONCLUSIONS:
    Their structures were proposed on the basis of spectroscopic data. The antibacterial and antioxidation activities were evaluated.