ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Chemistr of plant2016, 2016021195Mol Pharm.2017, 14(9):3164-3177Evid Based Complement Alternat Me...2017...Front Pharmacol.2017, 8:205PLoS One.2018, 13(3):e0193386Int J Mol Sci.2018, 19(9):E2825Food Quality and Safety2018, 2:213-219Evid Based Complement Alternat Me...2018...
Evid Based Complement Alternat Me...2018...Biol Pharm Bull.2018, 41(11):1645-1651Biol Pharm Bull.2018, 41(11):1685-1693Mol Cells.2018, 41(8):771-780Curr Eye Res.2018, 43(1):27-34Korean Journal of Pharmacognosy...2018...Front Immunol.2018, 9:2091Wageningen University & Research...2018...
Food and Agriculture Org. Of the ...2019...Neuropharmacology2019, 151437Chemistry of Plant Materials....2019...Pharmaceutical Chemistry Journal...2019...Sci Rep.2019, 9(1):4342Food and Chemical Toxicology...2020...Cell Metab.2020, S1550-4131(20)30002-4
Our products had been exported to the following research institutions and universities, And still growing.
The Ohio State University (USA)Michigan State University (USA)Universite Libre de Bruxelles (Belgium)National Chung Hsing University (Taiwan)
Universiti Putra Malaysia(UPM) (Malaysia)Sri Ramachandra University (India)Shanghai Institute of Organic C... (China)Technical University of Denmark (Denmark)
Sri Sai Aditya Institute of Pha... (India)Sant Gadge Baba Amravati Univer... (India)Universidade Federal de Pernamb... (Brazil)
Related Screening Libraries
||Periglaucine A inhibits hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells.|
|J Nat Prod. 2008 May;71(5):760-3. |
|Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus.[Pubmed: 18396905]|
METHODS AND RESULTS:
Four new hasubanane-type alkaloids, periglaucines A-D (1-4), and three known alkaloids, norruffscine (5), (-)-8-oxotetrahydropalmatine (6), and (-)-8-oxocanadine (7), were isolated from the aerial parts of Pericampylus glaucus. Their structures were elucidated on the basis of extensive NMR and EIMS data, and that of Periglaucine A (1) was confirmed by single-crystal X-ray diffraction.
Alkaloids 1-4 inhibited hepatitis B virus (HBV) surface antigen (HBsAg) secretion in Hep G2.2.15 cells. (-)-8-Oxotetrahydropalmatine (6) possessed a high selectivity index (SI = 22.4) for HBsAg secretion of the Hep G2.2.15 cell line with an IC(50) value of 0.14 mM.
Norruffscine (5) and (-)-8-oxotetrahydropalmatine (6) exhibited inhibitory activity against human immunodeficiency virus (HIV-1) with EC(50) values of 10.9 and 14.1 microM in C8166 cells (SI = 45.7 and 18.8), respectively.
Periglaucine A Description
||The aerial parts of Pericampylus glaucus
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.