ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Ind Crops Prod.2014, 62:173-178Molecules.2015, 20(11):20014-30J. Soc. Cosmet. Sci. Korea2016, 163-171J Pharm Biomed Anal.2017, 140:274-280Int J Mol Sci.2017, 18(12)Molecules.2017, 22(6)Chin. Med.J.Res. Prac.2017, 31(4)Pharm Biol.2017, 55(1):360-366
Pharmacol Rep.2017, 69(6):1224-1231J Nat Med.2017, 71(4):745-756J Nat Prod.2017, 80(4):854-863Front Aging Neurosci.2018, 10:269Industrial Crops and Products...2018...Sci Adv.2018, 4(10)Sci Rep.2018, 8:15059Biorxiv2019, 10.1101
Food Res Int.2019, 123:125-134Nutr Metab (Lond).2019, 16:31J Ethnopharmacol.2019, 235:406-414Molecules.2019, 24(11):E2044Molecules.2019, 24(22):E4022Chem Biol Interact.2019, 315:108910LWT-Food Sci Technol2020, 109163
Our products had been exported to the following research institutions and universities, And still growing.
Medical University of Gdansk (Poland)University of Maryland (USA)FORTH-IMBB (Greece)University Medical Center Mainz (Germany)
University of Maryland School o... (USA)Kyoto University (Japan)University of Hull (United Kingdom)Shanghai University of TCM (China)
Universidad de La Salle (Mexico)Universitas islam negeri Jakarta (Indonesia)Monash University (Australia)
Related Screening Libraries
||Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria methicillin-resistant Staphylococcus aureus (MRSA) and two strains of pathogenic bacteria methicillin-sensitive Staphylococcus aureus (MSSA).|
|Chinese Traditional\s&\sherbal Drugs, 2015,46 (6) :803-7. |
|Three bis-β-carboline alkaloids from Picrasma quassioides and their bioactivities[Reference: WebLink]|
|To study the chemical constituents from the stems of Picrasma quassioides.|
METHODS AND RESULTS:
The constituents were isolated and purified by silica gel, Sephadex LH-20, ODS column chromatographies, and preparative HPLC. Their structures were determined on the basis of their physicochemical properties and spectral data. The cytotoxic and antibacterial activities were assessed by MTT and MIC, respectively. Three β-carboline alkaloids were obtained from the 95% ethanol extract of the stems of P. quassioides and identified as picrasidine F (1), picrasidine G (2), and Picrasidine S (3). Compound 1 showed selective cytotoxicity to HeLa cell, while compounds 2 and 3 showed the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells. Compounds 1-3 showed the potent antibacterial activity against two strains of pathogenic bacteria methicillin-resistant Staphylococcus aureus (MRSA) and two strains of pathogenic bacteria methicillin-sensitive Staphylococcus aureus (MSSA).
The assignments of NMR data of compound 1 are reported in this paper for the first time. Compounds 1-3 show the potent cytotoxic and antibacterial activities.
Picrasidine S Description
||The root barks of Picrasma quassioides
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.