ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
BMC Complement Altern Med.2014, 14:242Molecules.2015, 20(11):20014-30Phytomedicine.2015, 22(11):1027-36J Agric Food Chem.2015, 63(44):9869-78Chemistr of plant2016, 2016021195Oncotarget.2016, 8(51):88386-88400J Ethnopharmacol.2017, 206:73-77Molecules.2017, 22(6)
Biol Pharm Bull.2017, 40(6):797-806Sci Rep.2017, 7(1):3249Food Res Int.2018, 106:909-919J Chromatogr B Analyt Technol Bio...2018...Lab Chip.2018, 18(6):971-978European Journal of Integrative M...2018...Evid Based Complement Alternat Me...2018...Biosci Rep.2018, 38(4)
J Sep Sci.2018, 41(11):2488-2497Phytomedicine.2018, 41:62-66Microb Pathog.2019, 131:128-134Molecules.2019, 24(4):E744Chem Biol Interact.2019, 298:1-7Chin J Appl. Physiol....2019...J Sep Sci.2020, 201901140
Our products had been exported to the following research institutions and universities, And still growing.
University of Indonesia (Indonesia)University of Wuerzburg (Germany)Chinese University of Hong Kong (China)Max Rubner-Institut (MRI) (Germany)
Mahidol University (Thailand)The University of Newcastle (Australia)John Innes Centre (United Kingdom)Monash University Sunway Campus (Malaysia)
Uniwersytet Gdański (Poland)Universita' Degli Studi Di Cagl... (Italy)MTT Agrifood Research Finland (Finland)
Related Screening Libraries
||S-adenosyl-L-methionine tosylate has a beneficial effect on the outcome of ischemic injury by reducing the blood-brain barrier (BBB) breakdown and neuronal death.|
|Brain Res Mol Brain Res. 1997 Feb;44(1):134-8. |
|Beneficial effects of S-adenosyl-L-methionine on blood-brain barrier breakdown and neuronal survival after transient cerebral ischemia in gerbils.[Pubmed: 9030707]|
|We have studied the beneficial effects of S-Adenosyl-L-methionine tosylate on blood-brain barrier (BBB) breakdown and neuronal survival after transient cerebral ischemia in gerbils.
METHODS AND RESULTS:
BBB breakdown experiments were performed in pentobarbital anesthetized gerbils subjected to 10 min of bilateral carotid artery occlusion and 6 h of reperfusion. For BBB breakdown measurements, S-adenosyl-L-methionine (120 mg/kg, i.p.) was administered to gerbils just after occlusion and thereafter every hour up to 5 h. Fluorometric measurements quantified the blood-brain permeability tracer, Evans blue (EB). S-adenosyl-L-methionine treatment significantly reduced the BBB breakdown as indicated by reduced levels of EB fluorescence. Neuronal count experiments were conducted in gerbils subjected to transient ischemia and 7 days of reperfusion. For neuronal count experiments S-adenosyl-L-methionine (15-120 mg/kg) was administered at 6 and 12 h after reperfusion, and twice each day thereafter for 7 days. S-adenosyl-L-methionine dose dependently protected the hippocampal CA1 neurons assessed by histopathological methods.
S-adenosyl-L-methionine has a beneficial effect on the outcome of ischemic injury by reducing the BBB breakdown and neuronal death.
S-Adenosyl-L-methionine tosylate Description
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.