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    Saikosaponin F
    Information
    CAS No. 62687-63-2 Price $368 / 20mg
    Catalog No.CFN90635Purity>=98%
    Molecular Weight929.14Type of CompoundTriterpenoids
    FormulaC48H80O17Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Our products had been exported to the following research institutions and universities, And still growing.
  • Instytut Nawozów Sztucznych w P... (Poland)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Martin Luther University of Hall... (Germany)
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  • Package
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    Biological Activity
    Description: Saikosaponin F shows anti-inflammatory effect against carrageenan-induced plantar oedema in the rat.
    Targets: Immunology & Inflammation related
    In vitro:
    Fitoterapia.1994, 65(5): 409-417.
    Anti-inflammatory and hepatoprotective activity of saikosaponin f and the root extract of Bupleurum kaoi[Reference: WebLink]
    A mixture of B. kaoi saponins, containing saikosaponin a, saikosaponin d and Saikosaponin F, showed anti-inflammatory effect against carrageenan-induced plantar oedema in the rat.
    METHODS AND RESULTS:
    The crude saponin mixture and Saikosaponin F exhibited a dose-dependent inhibiting effect. Antihepatotoxic activity was investigated in rats intoxicated with beta-D-galactosamine. Except for Saikosaponin F, administration of the other compounds significantly reduced the sGOT and sGPT levels.
    CONCLUSIONS:
    Pathological changes in rat hepatocytes such as inflammatory infiltration around the portal area, focal necrosis in the liver parenchyma, and hyaline degeneration, have been improved in all drugs treated groups.
    Saikosaponin F Description
    Source: The herbs of Bupleurum chinense DC.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.0763 mL 5.3813 mL 10.7626 mL 21.5253 mL 26.9066 mL
    5 mM 0.2153 mL 1.0763 mL 2.1525 mL 4.3051 mL 5.3813 mL
    10 mM 0.1076 mL 0.5381 mL 1.0763 mL 2.1525 mL 2.6907 mL
    50 mM 0.0215 mL 0.1076 mL 0.2153 mL 0.4305 mL 0.5381 mL
    100 mM 0.0108 mL 0.0538 mL 0.1076 mL 0.2153 mL 0.2691 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.