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Scutebata C
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Product Name Scutebata C
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CAS No.: 1207181-59-6
Catalog No.: CFN99324
Molecular Formula: C28H35NO9
Molecular Weight: 529.6 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Scutellaria barbata D.Don
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Scutebata B possesses a rare alpha-hydroxy group in its alpha,beta-unsaturated lactone rings.
In vitro:
Journal of Natural Products, 2010, 73(2):233-236.
Cytotoxic neoclerodane diterpenoids from Scutellaria barbata.[Reference: WebLink]

METHODS AND RESULTS:
Seven new neoclerodane diterpenoids, scutebata A, scutebata B, Scutebata C, scutebata D, scutebata E, scutebata F, scutebata G (1-7), have been isolated from Scutellaria barbata. Compounds 1-3 possess a rare alpha-hydroxy group in their alpha,beta-unsaturated lactone rings. Their structures were elucidated by spectroscopic analysis, and the relative configuration of scutebata A was deduced using ROESY data and the computational DFT method. Compounds 1, 2, 4, 5, and 6 were evaluated for in vitro cytotoxicity against six human cancer cell lines: HL-60, SMMC-7721, A-549, SK-BR-3, CACO-2, and PANC-1.
CONCLUSIONS:
Scutebata A (1) showed weak cytotoxicity against SK-BR-3 with an IC(50) value of 15.2 muM.
Scutebata C Description
Source: The herbs of Scutellaria barbata D.Don
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8882 mL 9.4411 mL 18.8822 mL 37.7644 mL 47.2054 mL
5 mM 0.3776 mL 1.8882 mL 3.7764 mL 7.5529 mL 9.4411 mL
10 mM 0.1888 mL 0.9441 mL 1.8882 mL 3.7764 mL 4.7205 mL
50 mM 0.0378 mL 0.1888 mL 0.3776 mL 0.7553 mL 0.9441 mL
100 mM 0.0189 mL 0.0944 mL 0.1888 mL 0.3776 mL 0.4721 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Chebulinic acid

Catalog No: CFN92296
CAS No: 18942-26-2
Price: $138/20mg
Glycycoumarin

Catalog No: CFN89408
CAS No: 94805-82-0
Price: $268/10mg
Kaurenoic acid

Catalog No: CFN97703
CAS No: 6730-83-2
Price: $80/20mg
Icariin

Catalog No: CFN99554
CAS No: 489-32-7
Price: $30/20mg
Colchicine

Catalog No: CFN99514
CAS No: 64-86-8
Price: $40/20mg
Pinostrobin chalcone

Catalog No: CFN99878
CAS No: 18956-15-5
Price: $368/20mg
Ginsenoside Rh1

Catalog No: CFN99970
CAS No: 63223-86-9
Price: $60/20mg
Licoricesaponin G2

Catalog No: CFN92915
CAS No: 118441-84-2
Price: $368/20mg
Zearalenone

Catalog No: CFN91172
CAS No: 17924-92-4
Price: $50/20mg
Silymarin

Catalog No: CFN99542
CAS No: 22888-70-6
Price: $30/20mg
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