ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: email@example.com
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $258.7 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
FEBS Lett.2015, 589(1):182-7J Pharm Biomed Anal.2016, 129:50-59Analytical sci. & Tech2016, 186-193Front Pharmacol.2016, 7:460Tea Res. Ins. Of China2017, 1-12Tropical J. of Pha. Research...2017...Journal of Life Science2017, 233-240Mol Cell.2017, 68(4):673-685
J Sep Sci.2018, 41(11):2488-2497BMB Rep.2018, 51(5):249-254Front Plant Sci.2018, 9:1424Front Immunol.2018, 9:2655Drug Invention Today...2019...Molecules.2019, 24(1):E159Cell Chem Biol.2019, 26(1):27-34Pak J Pharm Sci.2019, 32(6):2879-2885
FASEB J.2019, 33(8):9685-9694Chinese Pharmacological Bulletin...2019...J Sep Sci.2019, 42(21):3352-3362Int J Oncol.2019, 55(1):320-330Toxicol In Vitro.2019, 59:161-178Process Biochemistry2019, 87:213-220Biochem Biophys Res Commun....2020...
Our products had been exported to the following research institutions and universities, And still growing.
Srinakharinwirot University (Thailand)University of Leipzig (Germany)Istanbul University (Turkey)University of Liège (Belgium)
University of Padjajaran (Indonesia)Colorado State University (USA)Utah State University (USA)Universidad de Ciencias y Artes... (Mexico)
Universitas islam negeri Jakarta (Indonesia)China Medical University (Taiwan)Universidad Miguel Hernández (Spain)
Related Screening Libraries
||Soyasaponins(Aa, Ab, Af, Ba, Bb, and Bb') together with their derivatives may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase.|
| J.Agr.Food Chem., 2014, 62(9):2062-8. |
|Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase.[Pubmed: 24450802 ]|
|Soy (Glycine max, family Leguminosae), which contains isoflavones and saponins as main constituents, is known to exhibit memory-enhancing effects.
METHODS AND RESULTS:
Therefore, to investigate the role of soyasaponins in memory impairments, we isolated soyasaponin Ab (SA) and soyasaponin Bb (SB) from soybean and measured their protective effects against scopolamine-induced memory impairment in mice. SA and SB significantly prevented scopolamine-induced memory impairment in passive avoidance and Y-maze tasks. Compared to SA, SB rescued memory impairment more potently. Treatment with SB (10 mg/kg, p.o.) protected memory impairment in passive avoidance and Y-maze tasks to 97% (F = 68.10, P < 0.05) and 78% (F = 35.57, P < 0.05) of untreated normal control level, respectively. SA and SB (10 mg/kg) also rescued scopolamine-induced memory impairment in Morris water maze task (F = 14.51, P < 0.05). In addition, soyasaponins preserved brain-derived neurotrophic factor (BNDF) expression (F = 33.69, P < 0.05) and cAMP response element-binding (CREB) protein phosphorylation (F = 91.62, P < 0.05) in the hippocampus of scopolamine-treated mice. However, SA and SB did not inhibit acetylcholinesterase in vitro and ex vivo.
On the basis of these findings, we suggest that soybean, particularly soyasaponins, may protect memory impairment by increasing BDNF expression and CREB phosphorylation.
Soyasaponin Ba Description
||The seeds of Glycine max
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|《Journal of Medical Science Yanbian University》 2002-04 |
|Determination of soyasaponin Ba and Bb in Soybean Hypocotyl by high performance liquid chromatography[Reference: WebLink]|
|To establish a method for determination of Soyasaponin Ba and Bb.|
METHODS AND RESULTS:
Soyasaponin Ba and Bb were detected by a reversed-phase liquid chromatographic method. The method was proved to be linear in the range of 2 24～11 20μg and 2 35～11 80μg, and the intra-day coefficients of variation of assay for Soyasaponin Ba and Bb were 3 15% and 3 98%, respectively.
The method is accurate and reproducible, suitable for determination of Soyasaponin Ba and Bb.