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    Yadanzioside P
    Yadanzioside P
    Information
    CAS No. 79439-84-2 Price
    Catalog No.CFN96417Purity>=98%
    Molecular Weight710.72Type of CompoundDiterpenoids
    FormulaC34H46O16Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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  • Biological Activity
    Description: Yadanzioside P has antileukemic and antitumor activities.
    Yadanzioside P Description
    Source: The seeds of Brucea javanica.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.407 mL 7.0351 mL 14.0702 mL 28.1405 mL 35.1756 mL
    5 mM 0.2814 mL 1.407 mL 2.814 mL 5.6281 mL 7.0351 mL
    10 mM 0.1407 mL 0.7035 mL 1.407 mL 2.814 mL 3.5176 mL
    50 mM 0.0281 mL 0.1407 mL 0.2814 mL 0.5628 mL 0.7035 mL
    100 mM 0.0141 mL 0.0704 mL 0.1407 mL 0.2814 mL 0.3518 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Nat Prod. 1989 Mar-Apr;52(2):398-401.
    Antitumor agents, 104. Isolation of yadanziosides M and P from Brucea antidysenterica and identification of bruceantinoside B as a mixture of yadanzioside P and bruceantinoside C.[Pubmed: 2746262]

    METHODS AND RESULTS:
    Yadanzioside M [3] and Yadanzioside P [1] were isolated from Brucea antidysenterica. Their structures were elucidated by spectral data. Bruceantinoside B reported previously was reinvestigated and revealed to be a mixture of Yadanzioside P and bruceantinoside C [2].
    CONCLUSIONS:
    The structure of Yadanzioside P was found to be identical to that of bruceantinoside B.
    Chem Pharm Bull (Tokyo). 1986 Oct;34(10):4447-50.
    Yadanzioside P, a new antileukemic quassinoid glycoside from Brucea javanica (L.) Merr with the 3-O-(beta-D-glucopyranosyl)bruceantin structure.[Pubmed: 3829175]

    METHODS AND RESULTS:
    A new antileukemic quassinoid glycoside, Yadanzioside P, was isolated from "Ya-dan-zi", the seeds of Brucea javanica (L.) Merr. The structure was determined to be 3-O-(β-D-glucopyranosyl)-bruceantin by H- and C-NMR spectral measurement and enzymatic hydrolysis.
    CONCLUSIONS:
    The NMR spectral inspection indicates that a quassinoid glycoside formulated as 3-O-(β-D-glucopyranosyl)bruceantin is not bruceantinoside B, but Yadanzioside P.