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Bioactive Products
Toxicity Compound Library
A unique collection of 60 Toxicity natural compounds for screening
Catalog No: Bb201 Toxicity Compound Library
Screening Details
Size: 1mg/well * 60 Compounds
2mg/well * 60 Compounds
Cat. No. Information
CFN92862 3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol

3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol, one toxic terpenoid from raw Gansui. It has strong cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships.
CFN92863 Kansuinine A

Kansuinine A possesses analgesic props, it also shows NGF inducing activity.
CFN92864 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

3-O-(2′E,4′Z-decadienoyl)-20-O-acetylingenol, one toxic terpenoid from raw Gansui. It has strong cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships . It shows antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball. 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol induces the cytotoxicity of intestinal epithelial cells of rats (IEC-6 cells) depends on induction of cell apoptosis via mitochondrial pathway and cell cycle arrest.3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol, kansuinine B and kansuinine A can markedly promote SPL proliferation and NO production by PMphi at concentrations from 0.78 to 12.50 microg/mL, hence the they are believed to be important proinflammatory components of the roots of E. kansui.
CFN92866 Kansuinine B

Kansuinine B shows cytotoxic ,and analgesic activities, treatment with kansuinine B and kansuinine A represents a novel method to block the IL-6-induced effects.
CFN92867 3-O-(2'E,4'Z-Decadienoyl)ingenol

Kansuiphorin C and 3-O-(2′E,4′Z-decadienoyl)-ingenol exhibit significant anticomplement activity with respective 50% inhibitory concentration values of 44.1±3.8 and 89.5±5.5 uM. 20-O-acetyl-[3-O-(2'E,4'Z)-decadienoyl]-ingenol and 3-O-(2'E,4'Z)-decadienoylingenol show the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball.