Bioactive Products
| A unique collection of 60 Toxicity natural compounds for screening | ||
| Catalog No: | Bb201 | Toxicity Compound Library Screening Details |
| Size: | 1mg/well * 60 Compounds 2mg/well * 60 Compounds | |
| Cat. No. | Information |
| CFN92868 | 3-O-(2'E,4'E-Decadienoyl)ingenol 3-O-(2'E,4'E-Decadienoyl)ingenol , one toxic terpenoid from raw Gansui.3-O-(2′E,4′E-decadienoyl)-ingenol and 3-O-(2′E,4′Z-decadienoyl)-20-O-acetyl-ingenol show cytotoxicity on Namalwa cells with IC 50 values of 7.6 and 5.2 umol·L-1, respectively. |
| CFN97986 | Enniatin B1 Enniatin B1 has antifungal effects. It induces apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. Enniatin B1 also has intestinal toxicity. |
| CFN90610 | 7Beta-Hydroxycholesterol 7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells. 7beta-Hydroxycholesterol and 7-ketocholesterol have dual cytotoxic effects on the cells of the vascular wall by their ability to induce apoptosis in endothelial and smooth muscle cells and necrosis in fibroblasts. 7beta-Hydroxycholesterol can inhibit the proliferation of NCI-H460 cells through apoptosis via caspase activation. It can reinforce the susceptibility of K562 adriamycin-resistant cells to this drug, it also can enhance radiosensitivity in RDM4 cells. |
| CFN90660 | 3-Deoxyaconitine 3-Deoxyaconitine has toxicity. |
| CFN90756 | Carboxyatractyloside Carboxyatractyloside poisoning causes multiple organ dysfunction and can be fatal, the signs of a poor prognosis including coagulation abnormalities, hyponatraemia, marked hypoglycaemia, icterus and hepatic and renal failure, without antidote. Carboxyatractyloside can induce permeability transition, and that ageing induced mitochondrial DNA disruption and release of cytochrome c; it induces the inhibitory effect of tamoxifen on nonspecific membrane permeability. |
