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2. Pharmacological research
3. Inhibitors
[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $144.7 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Drug Dev Res.2020, doi: 10.1002Plants (Basel).2020, 9(11):1422.J Ethnopharmacol.2019, 236:31-41Life Sci.2018, 209:498-506Front Pharmacol.2021, 12:761922.Phytomedicine.2019, 61:152813Tea Res. Ins. Of China2017, 1-12Sci Rep. 2018, 1-9
Plants (Basel).2021, 10(6):1119.J Ethnopharmacol.2016, 192:370-381J of the Korean Society of Food S...2016...Korean J. Food Sci. & Technol....2022...International. J. of Food Propert...2017...J Pain Res.2022, 15:3469-3478.Vojnosanit Pregl2016, 75(00):391-391ACS Synth Biol.2020, 9(9):2282-2290.
Research on Crops.2017, 18(3):569South African J of Botany...2020...Front Pharmacol.2020, 11:566490.Key Engineering Materials...2022...Molecules.2021, 26(13):4081.FASEB J.2022, 36(7):e22387. Toxins (Basel).2020, 12(4):210.
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Our products had been exported to the following research institutions and universities, And still growing.
Universidade Federal de Pernamb... (Brazil)Korea Institute of Oriental Med... (Korea)Utah State University (USA)University of Melbourne (Australia)
John Innes Centre (United Kingdom)Srinakharinwirot University (Thailand)Korea Intitute of Science and T... (Korea)Research Unit Molecular Epigene... (Germany)
Colorado State University (USA)University of Vigo (Spain)Leibniz Institute of Plant Bioc... (Germany)
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[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one
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manager@chemfaces.com
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Plants (Basel).2021, 10(6):1119.Antioxidants (Basel).2022, 11(12):2411. J Agric Food Chem.2019, 67(27):7748-7754J Nat Med.2022, 76(1):59-67. Environ Toxicol Pharmacol.2019, 66:109-115Antioxidants (Basel).2020, 9(11):1121.Heinrich Heine University Dusseldorf2021, 62203.Molecules 2022, 27(3),960.Chem Biol Interact.2020, 328:109200.J Pharm Biomed Anal.2019, 172:268-277
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
Reference standards. |
[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one Description
| Source: |
The herbs of Curcuma phaeocaulis |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.811 mL |
19.0549 mL |
38.1098 mL |
76.2195 mL |
95.2744 mL |
| 5 mM |
0.7622 mL |
3.811 mL |
7.622 mL |
15.2439 mL |
19.0549 mL |
| 10 mM |
0.3811 mL |
1.9055 mL |
3.811 mL |
7.622 mL |
9.5274 mL |
| 50 mM |
0.0762 mL |
0.3811 mL |
0.7622 mL |
1.5244 mL |
1.9055 mL |
| 100 mM |
0.0381 mL |
0.1905 mL |
0.3811 mL |
0.7622 mL |
0.9527 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Fitoterapia. 2002 Feb;73(1):48-55. | | Furanosesquiterpenes from Commiphora sphaerocarpa and related adulterants of true myrrh.[Pubmed: 11864764] |
METHODS AND RESULTS:
A new furanosesquiterpene, (1E)-8,12-epoxygermacra-1,7,10,11-tetraen-6-one (3), was isolated from the resin of Commiphora sphaerocarpa together with the known compounds curzerenone (1), furanodienone (2), (1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one (4), [(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one (5), and dihydropyrocurzerenone (6).
CONCLUSIONS:
Hydrodistillates of the resins of C. sphaerocarpa, C. holtziana, C. kataf and C. myrrha were analysed. The identifications were aided by NMR, GC and GC-MS. |
|
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