ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $214.4 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Mediators Inflamm. 2016, 2016:6189590Phytother Res.2016, 30(12):2020-2026Oncol Rep.2016, 35(3):1356-64J Chromatogr B Analyt Technol Bio...2017...JPC-Journal of Planar Chromatogra...2017...J Chromatogr B Analyt Technol Bio...2019...APMIS.2019, 127(10):688-695Plant Physiol Biochem.2019, 144:355-364
J Adv Res.2019, 17:85-94J Pharm Biomed Anal.2019, 172:268-277BMC Complement Altern Med....2019...Int J Mol Sci.2019, 20(23):E6071Int J Mol Sci.2019, 20(8):E1855Molecules.2019, 24(16):E2985Molecules.2019, 24(16):E3003Molecules.2019, 24(6):E1177
Chemistry of Vegetable Raw Materi...2019...The Malaysian journal of patholog...2019...Planta Med.2019, 85(4):347-355Sci Rep.2019, 9:12132Appl. Sci.2020, 10(8),2804Int J Mol Med.2020, 45(5):1514-1524.Antioxidants (Basel).2020, 9(6):544.
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Our products had been exported to the following research institutions and universities, And still growing.
University of Queensland (Australia)Universite Libre de Bruxelles (Belgium)University of Wollongong (Australia)Technical University of Denmark (Denmark)
University of Otago (New Zealand)Northeast Normal University Cha... (China)Heidelberg University (Germany)Massachusetts General Hospital (USA)
Heinrich-Heine-University Düss... (Germany)University of Lodz (Poland)National Research Council of Ca... (Canada)
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3,4-O-dimethylcedrusin
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Biol Pharm Bull.2018, 41(1):65-72Asian Pac J Cancer Prev.2019, 20(1):65-72Tea Res. Ins. Of China2017, 1-12Food Res Int.2019, 123:125-134J Sep Sci.2018, 41(7):1682-1690Molecules.2020, 25(18),4089.Nutrients2020, 12(2):488Int J Pharmacol2020, 16:1-9Front Pharmacol.2017, 8:673Environ Toxicol.2020, doi: 10.1002
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Lignans Compound Library |
| Description: |
3',4-O-Dimethylcedrusin can improve wound healing in vivo by stimulating the formation of fibroblasts and collagen. |
| In vivo: |
| Phytomedicine, 1995, 2(1):17-22. | | In vivo wound healing activity of Dragon's Blood (Croton spp.), a traditional South American drug, and its constituents[Reference: WebLink] |
METHODS AND RESULTS:
The wound healing activity of dragon'sblood (Croton spp.), in Spanish ‚sangre de drago‛ or ‚sangre de grado‛, a traditional South American drug, and some of its constituents, including the alkaloid taspine (1), the dihydrobenzufuran lignan 3′,4-O-dimethylcedrusin (3,4-O-dimethylcedrusin,2) and proantho-cyanidins, was evaluated in vivo on rats, and compared with the wound healing actitivy of synthetic proanthocyanidins. The beneficial effect of dragon's blood on wound healing was confirmed. Dragon's blood stimulated contraction of the wound, formation of a crust, formation of new collagen, and regeneration of the epithelial layer.
3′,4-O-Dimethylcedrusin also improved wound healing in vivo by stimulating the formation of fibroblasts and collagen, but crude dragon's blood was more effective.
CONCLUSIONS:
This was due to the proanthocyanidins, present in dragon's blood, which stimulate contraction of the wound and precipitate with proteins forming a dark crust covering the wound, but which delay wound repair by a decreased formation of new fibroblasts. |
|
3,4-O-dimethylcedrusin Description
| Source: |
The peels of Magnolia officinalis |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.6709 mL |
13.3547 mL |
26.7094 mL |
53.4188 mL |
66.7735 mL |
| 5 mM |
0.5342 mL |
2.6709 mL |
5.3419 mL |
10.6838 mL |
13.3547 mL |
| 10 mM |
0.2671 mL |
1.3355 mL |
2.6709 mL |
5.3419 mL |
6.6774 mL |
| 50 mM |
0.0534 mL |
0.2671 mL |
0.5342 mL |
1.0684 mL |
1.3355 mL |
| 100 mM |
0.0267 mL |
0.1335 mL |
0.2671 mL |
0.5342 mL |
0.6677 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
