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    Natural Products
    1,2,5-Trihydroxyxanthone
    1,2,5-Trihydroxyxanthone
    Information
    CAS No. 156640-23-2 Price
    Catalog No.CFN89304Purity>=98%
    Molecular Weight244.20Type of CompoundXanthones
    FormulaC13H8O5Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    1,2,5-Trihydroxyxanthone

    1,2,5-Trihydroxyxanthone
    Product Name 1,2,5-Trihydroxyxanthone
    CAS No.: 156640-23-2
    Catalog No.: CFN89304
    Molecular Formula: C13H8O5
    Molecular Weight: 244.20 g/mol
    Purity: >=98%
    Type of Compound: Xanthones
    Physical Desc.: Powder
    Source: The barks of Garcinia tetralata.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
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  • Int J Mol Sci.2019, 20(9):E2244
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Antioxidants Compound Library
  • Xanthones Compound Library
  • Biological Activity
    Description: 1,2,5-Trihydroxyxanthone has antioxidative properties.
    In vitro:
    Phytochemistry, 1994, 36(2):501-506.
    Antioxidant xanthones from Garcinia subelliptica.[Reference: WebLink]

    METHODS AND RESULTS:
    From the woods of Garcinia subelliptica four new xanthones, garciniaxanthone C, 1,2,5-Trihydroxyxanthone, 2,6-dihydroxy-1,5-dimethoxyxanthone and 1,2-dihydroxy-5,6-dimethoxyxanthone have been isolated along with a new benzophenone derivative, 4′,6-dihydroxy-2,3′4-trimethoxybenzophenone. Their structures have been determined on the basis of mainly spectroscopic data and some chemical reactions.
    CONCLUSIONS:
    Antioxidative properties of all the isolated xanthones have been evaluated in vitro using three assay systems to measure antilipidperoxidation, free radical and superoxide anion scavenging activity.
    1,2,5-Trihydroxyxanthone Description
    Source: The barks of Garcinia tetralata.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.095 mL 20.475 mL 40.95 mL 81.9001 mL 102.3751 mL
    5 mM 0.819 mL 4.095 mL 8.19 mL 16.38 mL 20.475 mL
    10 mM 0.4095 mL 2.0475 mL 4.095 mL 8.19 mL 10.2375 mL
    50 mM 0.0819 mL 0.4095 mL 0.819 mL 1.638 mL 2.0475 mL
    100 mM 0.041 mL 0.2048 mL 0.4095 mL 0.819 mL 1.0238 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Phytochemistry. 1998 Nov;49(5):1395-402.
    Xanthones from Hypericum japonicum and H. henryi.[Pubmed: 9842731]

    METHODS AND RESULTS:
    From the aerial part of Hypericum japonicum, one new xanthone glycoside, 1,5-dihydroxyxanthone-6-O-beta-D-glucoside, one novel dimer xanthone, bijaponicaxanthone, and the first natural prenylated xanthone, 1,3,5,6-tetrahydroxy-4-prenylxanthone, were isolated together with the four known xanthones, 1,5,6-trihydroxyxanthone, isojacereubin, 6-deoxyisojacareubin and 4',5'-dihydro-1,5,6-trihydroxy-4',4',5'-trimethylfurano (2',3':4,5) xanthone. five previously known xanthones, kielcorin, cadensin, 1,7,-dihydroxyxanthone, 1,5-dihydroxy-4-methoxyxanthone and 1,2,5-Trihydroxyxanthone were also found in the dichoromethane extract of the stems and leaves of H. henryi. Their structures were elucidated by spectroscopic and chemical methods.
    CONCLUSIONS:
    Some of the compounds from H. japonicum were found to exert an interesting coagulant activity in an in vitro test. The chemotaxonomic value of xanthones is discussed briefly.
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