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1-Phenylbutane-1,3-dione
1-Phenylbutane-1,3-dione
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1-Phenylbutane-1,3-dione
Price: $30 / 20mg
CAS No.: 93-91-4
Catalog No.: CFN93103
Molecular Formula: C10H10O2
Molecular Weight: 162.2 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Canarium album
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: The starting 1-phenylbutane-1,3-dione is used as key intermediate for the synthesis of several new thiophene and pyrazole derivatives.
In vitro:
Pharmacology & Pharmacy, 2012 , 3 (2) :148-57.
Synthesis of Some New Arylazothiophene and Arylazopyrazole Derivatives as Antitumor Agents[Reference: WebLink]
The starting 1-Phenylbutane-1,3-dione (1) was used as key intermediate for the synthesis of several new thiophene and pyrazole derivatives.
METHODS AND RESULTS:
The newly synthesized compounds were evaluated for cytotoxicity against an Ehrlich ascites cells and cytotoxicity for compound 10d using EAC assay and 5-fluorouracil is used as reference drug. Compounds 7c, e and 10c, d showed significant activity in certain cancer cell and have been targeted for further studies, compound 10d is more effective and showed the highest activity. Structures of the newly prepared compounds were confirmed by both spectral, analytical data and molecular calculations.
1-Phenylbutane-1,3-dione Description
Source: The herbs of Canarium album
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.1652 mL 30.8261 mL 61.6523 mL 123.3046 mL 154.1307 mL
5 mM 1.233 mL 6.1652 mL 12.3305 mL 24.6609 mL 30.8261 mL
10 mM 0.6165 mL 3.0826 mL 6.1652 mL 12.3305 mL 15.4131 mL
50 mM 0.1233 mL 0.6165 mL 1.233 mL 2.4661 mL 3.0826 mL
100 mM 0.0617 mL 0.3083 mL 0.6165 mL 1.233 mL 1.5413 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Polyphyllin II

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Price: $/mg
Piperine

Catalog No: CFN99919
CAS No: 94-62-2
Price: $30/20mg
Ginsenoside Rg1

Catalog No: CFN99967
CAS No: 22427-39-0
Price: $40/20mg
Cannabidiolic acid

Catalog No: CFN99356
CAS No: 1244-58-2
Price: $413/5mg
Carnosic acid

Catalog No: CFN99102
CAS No: 3650-09-7
Price: $40/20mg
Ganoderic acid K

Catalog No: CFN92057
CAS No: 104700-95-0
Price: $318/5mg
Quercetin 3-O-rutinoside-(1->2)-O-...

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Isorhynchophylline

Catalog No: CFN96197
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