- ChemFaces is a professional high-purity natural products manufacturer.
- Product Intended Use
- 1. Reference standards
- 2. Pharmacological research
- 3. Inhibitors
3,3'',5-Triiodo-L-thyronine Sodium Salt
ChemFaces products have been cited in many studies from excellent and top scientific journals
Contact Us
Order & Inquiry & Tech Support
Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $15.4 / In-stock |
| Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Our products had been exported to the following research institutions and universities, And still growing.
- Amity University (India)
- University of Ioannina (Greece)
- Chulalongkorn University (Thailand)
- University of Medicine and Phar... (Romania)
- Institute of Pathophysiology Me... (Austria)
- Calcutta University (India)
- The Institute of Cancer Research (United Kingdom)
- University of Canterbury (New Zealand)
- Funda??o Universitária de Dese... (Brazil)
- University of Vienna (Austria)
- Wroclaw Medical University (Poland)
- More...
- The Journal of Korean Medicine2022, 43(3): 79-93.
- Int J Mol Sci.2022, 23(20):12516.
- J Nat Med.2017, 71(2):457-462
- J Food Composition and Analysis2022, 104417.
- RSC Advances2017, 86
- J Separation Science & Technology2016, 51:1579-1588
- Sci Rep.2021, 11(1):11936.
- Applied Biological Chem. 2020, 26(63).
- Phytomedicine.2019, 67:153159
- CZECH MYCOLOGY2021, 73(1):1-19.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
| Related Libraries |
|
| Description: |
The administration of 3,3'',5-Triiodo-L-thyronine Sodium Salt (T3) elicited a vasodilatation in C57BL/6 mice even at the lowest concentration (10(-9)M), a maximal relaxation of more than 50% was observed with the concentrations between 10(-9) and 10(-8)M. |
| Targets: |
Estrogen receptor | Antifection | Progestogen receptor |
| In vivo: |
| J Vasc Res. 2014;51(5):350-9. | | Vascular function of the mesenteric artery isolated from thyroid hormone receptor-α knockout mice.[Pubmed: 25500991] | This study evaluated the consequences of thyroid hormone receptor-α (TRα) disruption on vascular reactivity.
METHODS AND RESULTS:
The activity of superior mesenteric arteries isolated from TRα knockout mice generated in the SV129 background (TRα(0/0)SV) or in a pure C57BL/6 background (TRα(0/0)C57) was compared to that of their corresponding wild-type strains (SV129 or C57BL/6 mice).
The wild-type SV129 mice exhibited an impaired acetylcholine (Ach)-induced mesenteric artery relaxation compared to C57BL/6 mice, associated with greater responses to angiotensin II (AII) and phenylephrine (PE). The disruption of TRα decreased the vascular response to sodium nitroprusside and PE in both the SV129 and C57BL/6 genetic backgrounds. Responses to Ach and AII were also blunted, but only in TRα(0/0)C57 mice. The administration of 3,3'',5-Triiodo-L-thyronine Sodium Salt (T3) elicited a vasodilatation in C57BL/6 mice even at the lowest concentration (10(-9)M); a maximal relaxation of more than 50% was observed with the concentrations between 10(-9) and 10(-8)M. However, the response to T3 was nearly absent in TRα(0/0)C57 mice.
CONCLUSIONS:
TRα is essential for the control of vascular tone, particularly in thyroid hormone-mediated relaxation. The difference in response to Ach observed between the two wild-type mice should be taken into account for interpreting the vascular responses of genetically engineered mice. |
|
3,3'',5-Triiodo-L-thyronine Sodium Salt Description
| Source: |
|
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.486 mL |
7.4299 mL |
14.8597 mL |
29.7194 mL |
37.1493 mL |
| 5 mM |
0.2972 mL |
1.486 mL |
2.9719 mL |
5.9439 mL |
7.4299 mL |
| 10 mM |
0.1486 mL |
0.743 mL |
1.486 mL |
2.9719 mL |
3.7149 mL |
| 50 mM |
0.0297 mL |
0.1486 mL |
0.2972 mL |
0.5944 mL |
0.743 mL |
| 100 mM |
0.0149 mL |
0.0743 mL |
0.1486 mL |
0.2972 mL |
0.3715 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Tags: buy 3,3'',5-Triiodo-L-thyronine Sodium Salt | 3,3'',5-Triiodo-L-thyronine Sodium Salt supplier | purchase 3,3'',5-Triiodo-L-thyronine Sodium Salt | 3,3'',5-Triiodo-L-thyronine Sodium Salt cost | 3,3'',5-Triiodo-L-thyronine Sodium Salt manufacturer | order 3,3'',5-Triiodo-L-thyronine Sodium Salt | 3,3'',5-Triiodo-L-thyronine Sodium Salt distributor
