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    Natural Products
    3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan
    Information
    CAS No. 873867-94-8 Price
    Catalog No.CFN96935Purity>=98%
    Molecular Weight400.42Type of CompoundLignans
    FormulaC22H24O7Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

    3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan
    Product Name 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan
    CAS No.: 873867-94-8
    Catalog No.: CFN96935
    Molecular Formula: C22H24O7
    Molecular Weight: 400.42 g/mol
    Purity: >=98%
    Type of Compound: Lignans
    Physical Desc.: Powder
    Source: The roots of Artemisia absinthium.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • Biomed Sci Letters.2020, 26:319-326
  • Nat Prod Sci.2018, 24(2):109-114
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  • Rev. Chim.2020, 71(3),558-564
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
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  • Lignans Compound Library
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    Description: Reference standards.
    In vitro:
    Pharmaceutical Biology, 2008, 43(4):378-381.
    A New Larvicidal Lignan from Piper fimbriulatum.[Reference: WebLink]

    METHODS AND RESULTS:
    A new lignan, 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan (1) (6-[4-(3,4-dimethoxy-phenyl)-tetrahydro-furo[3,4-c.]furan-1-yl]-4-methoxy-benzo[] dioxole) together with two known lignans, 7′-epi.-sesartemin (2) and diayangambin (3), and a known flavonoid, 5-hydroxy-7,4′-dimethoxyflavone (4), were isolated from the leaves of Piper fimbriulatum. C. DC. Their structures were assigned by a combination of one- and two-dimensional NMR techniques.
    CONCLUSIONS:
    7′-epi.-Sesartemin (2) showed the highest larvicidal activity against Aedes aegypti. (LC100 17.6 µg/ml) and weak antiplasmodial (IC50 7.0 µg/ml) and antitrypanosomal (IC50 39.0 µg/ml) activities. None of the compounds was active against Leishmania mexicana..
    3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan Description
    Source: The roots of Artemisia absinthium.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.4974 mL 12.4869 mL 24.9738 mL 49.9476 mL 62.4344 mL
    5 mM 0.4995 mL 2.4974 mL 4.9948 mL 9.9895 mL 12.4869 mL
    10 mM 0.2497 mL 1.2487 mL 2.4974 mL 4.9948 mL 6.2434 mL
    50 mM 0.0499 mL 0.2497 mL 0.4995 mL 0.999 mL 1.2487 mL
    100 mM 0.025 mL 0.1249 mL 0.2497 mL 0.4995 mL 0.6243 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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