Science | Nature | Cell | View More
Natural Products
Mahuannin B
Mahuannin B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Mahuannin B
Price: $318 / 5mg
CAS No.: 82796-37-0
Catalog No.: CFN95554
Molecular Formula: C30H24O10
Molecular Weight: 544.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Ephedra spp.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $365.7 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • National Hellenic Research Foun... (Greece)
  • Chungnam National University (Korea)
  • Melbourne University (Australia)
  • Chiang Mai University (Thailand)
  • Medizinische Universit?t Wien (Austria)
  • University of Amsterdam (Netherlands)
  • Chang Gung University (Taiwan)
  • Yale University (USA)
  • Celltrion Chemical Research Ins... (Korea)
  • Institute of Pathophysiology Me... (Austria)
  • University of Zurich (Switzerland)
  • More...
Package
Featured Products
Malvidin-3-O-glucoside chloride

Catalog No: CFN92049
CAS No: 7228-78-6
Price: $238/10mg
Corilagin

Catalog No: CFN90176
CAS No: 23094-69-1
Price: $50/20mg
Linoleic acid

Catalog No: CFN93168
CAS No: 60-33-3
Price: $30/20mg
Genistin

Catalog No: CFN90250
CAS No: 529-59-9
Price: $40/20mg
Tannic acid

Catalog No: CFN90501
CAS No: 1401-55-4
Price: $40/20mg
Feretoside

Catalog No: CFN98330
CAS No: 27530-67-2
Price: $268/10mg
Nobiletin

Catalog No: CFN98726
CAS No: 478-01-3
Price: $30/20mg
Osthol

Catalog No: CFN98765
CAS No: 484-12-8
Price: $30/20mg
Trilobatin

Catalog No: CFN98658
CAS No: 4192-90-9
Price: $30/20mg
24-Methylenecycloartan-3-ol

Catalog No: CFN99496
CAS No: 1449-09-8
Price: $ /
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Mahuannin B is an effective anti-hydrotic agent, inhibiting the production of cAMP via suppression of adenylate cyclase (AC) activity.
Mahuannin B Description
Source: The herbs of Ephedra spp.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Benzyl beta-D-glucopyranoside

Catalog No: CFN95427
CAS No: 4304-12-5
Price: $318/10mg
Decursitin D

Catalog No: CFN95002
CAS No: 245446-61-1
Price: $388/5mg
Tortoside B (Manglieside E)

Catalog No: CFN95390
CAS No: 190655-17-5
Price: $413/5mg
Naringin 6''-acetate

Catalog No: CFN95418
CAS No: 139934-60-4
Price: $318/5mg
New compound 19

Catalog No: CFN95538
CAS No: N/A
Price: $413/5mg
Giganteone A

Catalog No: CFN95481
CAS No: 460337-13-7
Price: $318/5mg
5,7,2',4'-Tetrahydroxy-8,3'-di(gam...

Catalog No: CFN95084
CAS No: 141846-47-1
Price: $413/5mg
cis-Mulberroside A

Catalog No: CFN95006
CAS No: 166734-06-1
Price: $418/10mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8365 mL 9.1827 mL 18.3655 mL 36.7309 mL 45.9137 mL
5 mM 0.3673 mL 1.8365 mL 3.6731 mL 7.3462 mL 9.1827 mL
10 mM 0.1837 mL 0.9183 mL 1.8365 mL 3.6731 mL 4.5914 mL
50 mM 0.0367 mL 0.1837 mL 0.3673 mL 0.7346 mL 0.9183 mL
100 mM 0.0184 mL 0.0918 mL 0.1837 mL 0.3673 mL 0.4591 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Kinase Assay:
Phytomedicine . 2017 Jul 1;30:18-27.
Mahuannin B an adenylate cyclase inhibitor attenuates hyperhidrosis via suppressing β2-adrenoceptor/cAMP signaling pathway[Pubmed: 28545666]
Background: Based on the traditional application of traditional Chinese Medicines (TCMs), Ephedra Herba (EH) is used to cure cold fever by inducing sweating, whereas Ephedra Radix (ER) is used to treat hyperhidrosis. Although they come from the same plant, Ephedra sinica Stapf, but have play opposing roles in clinical applications. EH is known to contain ephedrine alkaloids, which is the driver of the physiological changes in sweating, heart rate and blood pressure. However, the active pharmacological ingredients (APIs) of ER and the mechanisms by which it restricts sweating remain unknown. Purpose: The current work aims to discover the hidroschesis APIs from ER, as well as to establish its action mechanism. Methods: UPLC-Q/TOF-MS, PCA, and heat map were utilized for identifying the differences between EH and ER. HPLC integrated with a β2-adrenoceptor (β2-AR) activity luciferase reporter assay system was used to screen active inhibitors; molecular docking and a series of biological assays centered on β2-AR-related signaling pathways were evaluated to understand the roles of APIs. Results: The opposite effect on sweating of EH and ER can be attributed to the APIs of amphetamine-type alkaloids and flavonoid derivatives. Mahuannin B is an effective anti-hydrotic agent, inhibiting the production of cAMP via suppression of adenylate cyclase (AC) activity. Conclusion: The effects of EH and ER on sweat and β2-AR-related signaling pathway are opposite due to different alkaloids and flavonoids of APIs in EH and ER. The present work not only sheds light on the hidroschesis action of Mahuannin B, but also presents a potential target of AC in the treatment of hyperhidrosis.
Malvidin-3-O-glucoside chloride

Catalog No: CFN92049
CAS No: 7228-78-6
Price: $238/10mg
Corilagin

Catalog No: CFN90176
CAS No: 23094-69-1
Price: $50/20mg
Linoleic acid

Catalog No: CFN93168
CAS No: 60-33-3
Price: $30/20mg
Genistin

Catalog No: CFN90250
CAS No: 529-59-9
Price: $40/20mg
Tannic acid

Catalog No: CFN90501
CAS No: 1401-55-4
Price: $40/20mg
Feretoside

Catalog No: CFN98330
CAS No: 27530-67-2
Price: $268/10mg
Nobiletin

Catalog No: CFN98726
CAS No: 478-01-3
Price: $30/20mg
Osthol

Catalog No: CFN98765
CAS No: 484-12-8
Price: $30/20mg
Trilobatin

Catalog No: CFN98658
CAS No: 4192-90-9
Price: $30/20mg
24-Methylenecycloartan-3-ol

Catalog No: CFN99496
CAS No: 1449-09-8
Price: $ /
Tags: buy Mahuannin B | Mahuannin B supplier | purchase Mahuannin B | Mahuannin B cost | Mahuannin B manufacturer | order Mahuannin B | Mahuannin B distributor