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    Natural Products
    3,8'-Biapigenin
    3,8'-Biapigenin
    Information
    CAS No. 101140-06-1 Price $368 / 5mg
    Catalog No.CFN99025Purity>=98%
    Molecular Weight538.5 Type of CompoundFlavonoids
    FormulaC30H18O10Physical DescriptionYellow powder
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $423.2 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    3,8'-Biapigenin

    3,8'-Biapigenin
    Product Name 3,8'-Biapigenin
    CAS No.: 101140-06-1
    Catalog No.: CFN99025
    Molecular Formula: C30H18O10
    Molecular Weight: 538.5 g/mol
    Purity: >=98%
    Type of Compound: Flavonoids
    Physical Desc.: Yellow powder
    Targets: ROS
    Source: The herbs of Hypericum perforatum L.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $368 / 5mg
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  • Molecules.2017, 22(11)
  • Journal of Chromatography A2020, 460942
  • Biochem Biophys Res Commun.2020, 522(4):1052-1058
  • Pharm Biol.2017, 55(1):360-366
  • Int J Oncol.2016, 49(4):1497-504
  • J Chromatogr A.2017, 1518:46-58
  • J Ethnopharmacol.2017, 206:327-336
  • Phytomedicine.2018, 47:48-57
  • Anal Chim Acta.2018, 1039:162-171
  • Chinese Pharmacological Bulletin2019, 35(8):1120-1125
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Antioxidants Compound Library
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  • Biological Activity
    Description: 3, 8''-Biapigenin can modulate intracellular ROS production.
    Targets: ROS
    In vitro:
    Phytochemistry. 2009 Jan;70(2):244-9.
    Cellular reactive oxygen species inhibitory constituents of Hypericum thasium Griseb.[Pubmed: 19203769 ]

    METHODS AND RESULTS:
    The phytochemical investigation of the ethyl acetate extract of Hypericum thasium has led to the characterization of four benzophenone derivatives 1-4, a known benzophenone 5 and four known flavonoids, quercetin (6), quercitrin (7), isoquercetin (8), and 3,8'-Biapigenin (9). Lucigenin- and luminal-based chemiluminescence assays were employed to monitor the inhibitory activity of these compounds towards the production of reactive oxygen species (ROS) by human polymorphoneutrophils (PMNs).
    CONCLUSIONS:
    The assay results showed that benzophenones 1 and 3 are extracellular inhibitors of ROS production, while flavonoids 6, 8, and 9 can modulate intracellular ROS production.
    3,8'-Biapigenin Description
    Source: The herbs of Hypericum perforatum L.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.857 mL 9.2851 mL 18.5701 mL 37.1402 mL 46.4253 mL
    5 mM 0.3714 mL 1.857 mL 3.714 mL 7.428 mL 9.2851 mL
    10 mM 0.1857 mL 0.9285 mL 1.857 mL 3.714 mL 4.6425 mL
    50 mM 0.0371 mL 0.1857 mL 0.3714 mL 0.7428 mL 0.9285 mL
    100 mM 0.0186 mL 0.0929 mL 0.1857 mL 0.3714 mL 0.4643 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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