Info: More News
Science | Nature | Cell | View More
Natural Products
3-O-Feruloylquinic acid
Information
CAS No. 1899-29-2 Price
Catalog No.CFN92393Purity>=98%
Molecular Weight368.3Type of CompoundPhenylpropanoids
FormulaC17H20O9Physical DescriptionPowder
Download COA    MSDS    SDF    ManualSimilar structuralComparison (Web)  (SDF)
Citing Use of our Products
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Ain Shams University (Egypt)
  • Universidade do Porto (Portugal)
  • Weizmann Institute of Science (Israel)
  • Max-Planck-Insitut (Germany)
  • Leibniz-Institut für Pflanzenb... (Germany)
  • University of Bordeaux (France)
  • National Cancer Institute (USA)
  • The Ohio State University (USA)
  • Macau University of Science and... (China)
  • Celltrion Chemical Research Ins... (Korea)
  • Uniwersytet Jagielloński w Kra... (Poland)
  • More...
  • Package
    Featured Products
    Ginsenoside Compound K

    Catalog No: CFN99756
    CAS No: 39262-14-1
    Price: $30/20mg
    Ganoderol B

    Catalog No: CFN99064
    CAS No: 104700-96-1
    Price: $318/5mg
    Deapi-platycodin D3

    Catalog No: CFN92269
    CAS No: 67884-05-3
    Price: $238/5mg
    6',7'-Dihydroxybergamottin

    Catalog No: CFN98307
    CAS No: 264234-05-1
    Price: $318/10mg
    Ganoderol A

    Catalog No: CFN99065
    CAS No: 104700-97-2
    Price: $338/5mg
    Ganoderenic acid D

    Catalog No: CFN90300
    CAS No: 100665-43-8
    Price: $368/20mg
    3-O-Caffeoylquinic acid methyl ester

    Catalog No: CFN92573
    CAS No: 123483-19-2
    Price: $268/20mg

    3-O-Feruloylquinic acid

    3-O-Feruloylquinic acid
    Product Name 3-O-Feruloylquinic acid
    CAS No.: 1899-29-2
    Catalog No.: CFN92393
    Molecular Formula: C17H20O9
    Molecular Weight: 368.3 g/mol
    Purity: >=98%
    Type of Compound: Phenylpropanoids
    Physical Desc.: Powder
    Targets: Antifection | Proteasome | H5N1
    Source: The fruits of Coffea canephorra var. Robusta
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price:
    Download: COA    MSDS    SDF    Manual
    Similar structural: Comparison (Web)  (SDF)
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
    product package
  • J Nat Med.2018, 72(3):734-744
  • J Nat Prod.2015, 78(6):1339-4
  • Phytochemistry.2021, 181:112539.
  • Eur J Pharmacol.2022, 917:174744.
  • Oxid Med Cell Longev.2022, 2022:9139338.
  • Int Immunopharmacol.2022, 106:108603.
  • Int J Mol Sci.2022, 23(23):14545.
  • J Cell Biochem.2022, 123(7):1222-1236.
  • Biomed Pharmacother.2020, 125:109784.
  • Wageningen University & Research2018, January 2018
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
    Biological Activity
    Description: 3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.
    Targets: Antifection | Proteasome | H5N1
    In vitro:
    Food Funct. 2013 Nov;4(11):1632-8.
    Isolation and quantification of major chlorogenic acids in three major instant coffee brands and their potential effects on H2O2-induced mitochondrial membrane depolarization and apoptosis in PC-12 cells.[Pubmed: 24061869]
    Coffee is a most consumed drink worldwide, with potential health effects on several chronic diseases including neuronal degenerative diseases. Chlorogenic acids (CHAs) are phenolic compounds found in coffee and they are reported to have strong antioxidant and anti-inflammatory activities. However, the amounts of CHAs often vary in coffee drinks and their potential effects on ROS-induced neuronal cell death still require more investigation.
    METHODS AND RESULTS:
    Therefore, in this paper, major CHAs were isolated from three major instant coffee brands, confirmed and quantified using HPLC and NMR spectroscopic methods. Then, their antioxidant activities and protective effects on H2O2-induced apoptosis in PC-12 cells were investigated using radical scavenging, mitochondrial membrane potential and caspase assays. In the coffee samples, three major CHAs (3-O-caffeoylquinic acid, 4-O-caffeoylquinic acid, 5-O-caffeoylquinic acid) and some minor CHAs (3-O-Feruloylquinic acid, 4-O-feruloylquinic acid, 5-O-feruloylquinic acid, 3,5-O-dicaffeoylquinic acid, 3,4-O-dicaffeoylquinic acid, and 4,5-O-dicaffeoylquinic acid) were detected. The three major CHAs were further isolated and their chemical structures were confirmed using NMR spectroscopic techniques. Also, the amounts of the three major CHAs were individually quantified using a HPLC method. At the concentration of 10 μM, all three major CHAs quenched DPPH and/or xanthine oxidase-generated radical species by 21-51% (P < 0.014). They also inhibited H2O2-induced mitochondrial membrane depolarization and caspase-9 activation by 27% (P < 0.034) and 50% (P < 0.05), respectively.
    CONCLUSIONS:
    This study suggests that the major CHAs found in coffee are likely to be potent antioxidant compounds able to quench radical species as well as inhibit H2O2-induced apoptosis via suppressing mitochondrial membrane depolarization and caspase-9 activation in the cells.
    Yao Xue Xue Bao. 2015 Feb;50(2):207-10.
    Chemical constituents of the roots of Macleaya microcarpa and activation efficacy of benzophenanthridine alkaloids for the transcription of xbp1 gene.[Pubmed: 25975030]
    Ongoing study on the chemical constituents of the roots of Macleaya microcarpa led to the isolation of eight compounds of derivatives of triterpenes and organic acids in addition to some previously identified benzophenanthridines.
    METHODS AND RESULTS:
    The eight compounds were identified by spectroscopic methods as well as comparison with literature values as 1-oxo-2, 22 (30)-hopandien-29-oic acid (1), 3-oxo-12-oleanen-30-oic acid (2), 3α-hydroxy-12-oleanen-30-oic acid (3), 3β-hydroxy-12-oleanen-30-oic acid (4), ferulic acid (5), ferulic acid 4-O-β-D-glucoside (6), 3-O-Feruloylquinic acid (7), and methyl 3-O-feruloylquinate (8). Of which, 1 is a new triterpenoid of hopanes and 2-8 are isolated from M microcarpa for the first time. In order to discover natural active compounds as potential agents of anti-ulcerative colitis (UC), an in vitro drug high-throughput screening model targeted x-box-binding protein 1 (xbp1) was employed to evaluate the activity of the major chemical constituents of M microcarpa.
    CONCLUSIONS:
    The result confirmed that two dihydrobenzophenanthridines, dihydrosanguinarine (9) and dihydrochelerythrine (10), showed a certain activity on activating the transcription of xbpl, a transcription factor (TF) associated with the occurrence, development, and potential treatment of UC, with their relative activating ratios being 1.76 and 1.77 times, respectively, as compared with control group.
    3-O-Feruloylquinic acid Description
    Source: The fruits of Coffea canephorra var. Robusta
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    Barbaloin-related compound B

    Catalog No: CFN95455
    CAS No: 473225-22-8
    Price: $318/5mg
    Ganoderic acid L

    Catalog No: CFN95022
    CAS No: 102607-24-9
    Price: $413/5mg
    Ginsenoside Rd2 (Quinquenoside L10...

    Catalog No: CFN95231
    CAS No: 83480-64-2
    Price: $318/10mg
    Fortunellin-6''-beta-D-glucopyrano...

    Catalog No: CFN95315
    CAS No: 1218774-64-1
    Price: $318/5mg
    N-trans-caffeoyltyramine

    Catalog No: CFN95265
    CAS No: 103188-48-3
    Price: $318/5mg
    ent-16beta,17-dihydroxy-9(11)-kaur...

    Catalog No: CFN95172
    CAS No: 55483-24-4
    Price: $318/10mg
    6-Methoxyfraxinellone

    Catalog No: CFN95485
    CAS No: N/A
    Price: $318/10mg
    Kihadanin D

    Catalog No: CFN95482
    CAS No: 2770024-83-2
    Price: $413/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.7152 mL 13.5759 mL 27.1518 mL 54.3036 mL 67.8794 mL
    5 mM 0.543 mL 2.7152 mL 5.4304 mL 10.8607 mL 13.5759 mL
    10 mM 0.2715 mL 1.3576 mL 2.7152 mL 5.4304 mL 6.7879 mL
    50 mM 0.0543 mL 0.2715 mL 0.543 mL 1.0861 mL 1.3576 mL
    100 mM 0.0272 mL 0.1358 mL 0.2715 mL 0.543 mL 0.6788 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Ginsenoside Compound K

    Catalog No: CFN99756
    CAS No: 39262-14-1
    Price: $30/20mg
    Ganoderol B

    Catalog No: CFN99064
    CAS No: 104700-96-1
    Price: $318/5mg
    Deapi-platycodin D3

    Catalog No: CFN92269
    CAS No: 67884-05-3
    Price: $238/5mg
    6',7'-Dihydroxybergamottin

    Catalog No: CFN98307
    CAS No: 264234-05-1
    Price: $318/10mg
    Ganoderol A

    Catalog No: CFN99065
    CAS No: 104700-97-2
    Price: $338/5mg
    Ganoderenic acid D

    Catalog No: CFN90300
    CAS No: 100665-43-8
    Price: $368/20mg
    3-O-Caffeoylquinic acid methyl ester

    Catalog No: CFN92573
    CAS No: 123483-19-2
    Price: $268/20mg
    Tags: buy 3-O-Feruloylquinic acid | 3-O-Feruloylquinic acid supplier | purchase 3-O-Feruloylquinic acid | 3-O-Feruloylquinic acid cost | 3-O-Feruloylquinic acid manufacturer | order 3-O-Feruloylquinic acid | 3-O-Feruloylquinic acid distributor