Science | Nature | Cell | View More
Natural Products
5,7-Dihydroxy-3',4',5'-trimethoxyflavone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 5,7-Dihydroxy-3',4',5'-trimethoxyflavone
Price:
CAS No.: 18103-42-9
Catalog No.: CFN96493
Molecular Formula: C18H16O7
Molecular Weight: 344.32 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Centaurea scoparia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Charles Sturt University (Denmark)
  • University of South Australia (Australia)
  • VIT University (India)
  • Imperial College London (United Kingdom)
  • CSIRO - Agriculture Flagship (Australia)
  • Universidade Federal de Goias (... (Brazil)
  • University of Melbourne (Australia)
  • Sanford Burnham Prebys Medical ... (USA)
  • Harvard University (USA)
  • Chulalongkorn University (Thailand)
  • Gyeongsang National University (Korea)
  • More...
Package
Featured Products
1-O-Acetyl britannilactone

Catalog No: CFN90219
CAS No: 681457-46-5
Price: $338/20mg
Allantoin

Catalog No: CFN97557
CAS No: 97-59-6
Price: $30/20mg
trans-3-Oxo-alpha-ionol

Catalog No: CFN92428
CAS No: 896107-70-3
Price: $ / mg
Alisol O

Catalog No: CFN92404
CAS No: 928148-51-0
Price: $ / mg
Berbamine

Catalog No: CFN98727
CAS No: 478-61-5
Price: $50/20mg
(-)-Epigallocatechin gallate

Catalog No: CFN99569
CAS No: 989-51-5
Price: $40/20mg
11-Oxomogroside III

Catalog No: CFN92192
CAS No: 952481-53-7
Price: $318/10mg
Cyclo(Pro-Leu)

Catalog No: CFN90281
CAS No: 5654-86-4
Price: $238/10mg
Cucurbitacin B

Catalog No: CFN99129
CAS No: 6199-67-3
Price: $70/20mg
Neoglucobrassicin

Catalog No: CFN00503
CAS No: 5187-84-8
Price: $ / mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 5,7-Dihydroxy-3',4',5'-trimethoxyflavone is a natural product from Centaurea scoparia.
In vitro:
ScientificWorldJournal. 2014;2014:274207.
Cytotoxic activities of flavonoids from Centaurea scoparia.[Pubmed: 25114960 ]

METHODS AND RESULTS:
Phytochemical studies on the ethanolic extract of the aerial parts of Centaurea scoparia led to the isolation of two new flavonoids, 3',4'-dihydroxy-(3'',4''-dihydro-3''-hydroxy-4''-acetoxy)-2'',2''-dimethylpyrano-(5'',6'':7,8)-flavone-3-O- β -D-glucopyranoside (1) and 3,3',4'-trihydroxy-(3'',4''-dihydro-3'',4''-dihydroxy)-2'',2''-dimethylpyrano-(5'',6'':7,8)-flavone (2), along with eight known flavonoids isolated for the first time from this plant, cynaroside (3), Apigetrin (4), centaureidin (5), oroxylin A (6), 5,7-Dihydroxy-3',4',5'-trimethoxyflavone (7), atalantoflavone (8), 5-hydroxy-3',4',8-trimethoxy-2'',2''-dimethylpyrano (5'',6'':6,7)-flavone (9), and 3',4',5,8-tetramethoxy-2'',2''-dimethylpyrano (5'',6'':6,7)-flavone (10). The structures of the isolated compounds were elucidated by means of spectroscopic tools including 1D and 2D NMR, UV, IR, and mass spectroscopy.
CONCLUSIONS:
Cytotoxic activities of the isolated compounds were evaluated against human cervical carcinoma HeLa, human hepatocellular carcinoma HepG2, and human breast carcinoma MCF-7. Compound 2 was the most potent cytotoxic agent against HeLa cells with an IC50 0.079  μM.
5,7-Dihydroxy-3',4',5'-trimethoxyflavone Description
Source: The herbs of Centaurea scoparia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Cyclocurcumin

Catalog No: CFN95103
CAS No: 153127-42-5
Price: $338/10mg
Fortunellin-6''-beta-D-glucopyrano...

Catalog No: CFN95315
CAS No: 1218774-64-1
Price: $318/5mg
New compound 16

Catalog No: CFN95465
CAS No: N/A
Price: $413/5mg
Clemomandshuricoside B

Catalog No: CFN95302
CAS No: 905294-48-6
Price: $318/10mg
Quercetin 3-O-beta-(6''-p-coumaroy...

Catalog No: CFN95088
CAS No: 143061-65-8
Price: $338/10mg
[(1(10)E,2R,4R)]-2-Methoxy-8,12-ep...

Catalog No: CFN95198
CAS No: 75412-95-2
Price: $318/10mg
(-)-5'-Methoxyisolariciresinol 3al...

Catalog No: CFN95403
CAS No: 143236-03-7
Price: $318/5mg
Cannabisin P

Catalog No: CFN95456
CAS No: 2756983-19-2
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9043 mL 14.5214 mL 29.0428 mL 58.0855 mL 72.6069 mL
5 mM 0.5809 mL 2.9043 mL 5.8086 mL 11.6171 mL 14.5214 mL
10 mM 0.2904 mL 1.4521 mL 2.9043 mL 5.8086 mL 7.2607 mL
50 mM 0.0581 mL 0.2904 mL 0.5809 mL 1.1617 mL 1.4521 mL
100 mM 0.029 mL 0.1452 mL 0.2904 mL 0.5809 mL 0.7261 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
1-O-Acetyl britannilactone

Catalog No: CFN90219
CAS No: 681457-46-5
Price: $338/20mg
Allantoin

Catalog No: CFN97557
CAS No: 97-59-6
Price: $30/20mg
trans-3-Oxo-alpha-ionol

Catalog No: CFN92428
CAS No: 896107-70-3
Price: $ / mg
Alisol O

Catalog No: CFN92404
CAS No: 928148-51-0
Price: $ / mg
Berbamine

Catalog No: CFN98727
CAS No: 478-61-5
Price: $50/20mg
(-)-Epigallocatechin gallate

Catalog No: CFN99569
CAS No: 989-51-5
Price: $40/20mg
11-Oxomogroside III

Catalog No: CFN92192
CAS No: 952481-53-7
Price: $318/10mg
Cyclo(Pro-Leu)

Catalog No: CFN90281
CAS No: 5654-86-4
Price: $238/10mg
Cucurbitacin B

Catalog No: CFN99129
CAS No: 6199-67-3
Price: $70/20mg
Neoglucobrassicin

Catalog No: CFN00503
CAS No: 5187-84-8
Price: $ / mg
Tags: buy 5,7-Dihydroxy-3',4',5'-trimethoxyflavone | 5,7-Dihydroxy-3',4',5'-trimethoxyflavone supplier | purchase 5,7-Dihydroxy-3',4',5'-trimethoxyflavone | 5,7-Dihydroxy-3',4',5'-trimethoxyflavone cost | 5,7-Dihydroxy-3',4',5'-trimethoxyflavone manufacturer | order 5,7-Dihydroxy-3',4',5'-trimethoxyflavone | 5,7-Dihydroxy-3',4',5'-trimethoxyflavone distributor