ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Inflammation2015, 38(1):445-55Mol Cells.2015, 38(9):765-72J Ethnopharmacol.2016, 194:219-227Oncol Rep.2016, 35(3):1356-64US20170000760 A12016, 42740Braz J Med Biol Res. 2016, 49(7)Planta Med.2016, 82(13):1208-16Phytochemistry.2017, 141:162-170
Pharm Biol.2017, 55(1):360-366Integr Cancer Ther.2018, 17(3):832-843BMC Pharmacol Toxicol.2018, 19(1):5J Ethnopharmacol.2019, 235:406-414Pak J Pharm Sci.2019, 32(6):2879-2885Srinagarind Medical Journal2019, 34(1)J Sep Sci.2020, 201901140Internoational J of Toxicology...2020...
Nutrients.2020, 12(3):595.Biomed Pharmacother.2020, 131:110673.Int J Mol Sci.2020, 21(8):2790.Int J Mol Sci.2020, 21(9):3392. Food Chem.2020, 327:126992.J Agric Food Chem....2020...Molecules.2021, 26(2):E255.
Our products had been exported to the following research institutions and universities, And still growing.
Lund University (Sweden)Charles Sturt University (Denmark)Universidade Federal de Pernamb... (Brazil)Agricultural Research Organizat... (Israel)
Medical University of South Car... (USA)Aveiro University (Portugal)Kyoto University (Japan)Universidad de La Salle (Mexico)
University of Hertfordshire (United Kingdom)Chiang Mai University (Thailand)Medizinische Universit?t Wien (Austria)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Anal Bioanal Chem.2018, 410(5):1561-1569Food Chem.2020, 327:126992.Microb Pathog.2019, 131:128-134Food Chem.2017, 221:1135-1144Biomed Chromatogr.2016, 30(10):1573-81J Biol Chem.2014, 289(3):1723-31Molecules.2018, 23(12):E3103Antioxidants (Basel).2020, 9(4):326. UDC.2020, 19(4).Anal Chim Acta.2018, 1039:162-171
Related Screening Libraries
||6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.|
|Molecules, 2007, 12(1):86-97. |
|Inhibitory effects of 5,6,7-trihydroxyflavones on tyrosinase.[Pubmed: 17693955]|
METHODS AND RESULTS:
Baicalein (1), 6-Hydroxyapigenin (6), 6-hydroxygalangin (13) and 6-hydroxy-kaempferol (14), which are naturally occurring flavonoids from a set of 14 hydroxy-flavones tested, exhibited high inhibitory effects on tyrosinase with respect to L-DOPA, while each of the 5,6,7-trihydroxyflavones 1, 6, 13 or 14 acted as a cofactor to monophenolase. Moreover, 6-Hydroxykaempferol (14) showed the highest activity and was a competitive inhibitor of tyrosinase compared to L-DOPA. 5,6,7-Trihydroxyflavones 1, 6, 13 or 14 showed also high antioxidant activities.
Hence, we conclude that the 5,6,7-trihydroxy-flavones are useful as good depigmentation agents with inhibitory effects in addition to their antioxidant properties.
||The herbs of Inula japonica Thunb.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|6-hydroxykaempferol and its glycosides from Carthamus tinctorius petals.[Reference: WebLink]|
METHODS AND RESULTS:
From the dried petals of Carthamus tinctorius, five flavonoids, 6-Hydroxykaempferol, 6-Hydroxykaempferol 3-glucoside, 6-Hydroxykaempferol 3,6-diglucoside, 6-Hydroxykaempferol 3,6,7-triglucoside and 6-Hydroxykaempferol 3-rutinoside-6-glucoside, were isolated along with 13 known compounds, and their structures determined by spectroscopic means including 2D NMR.