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2. Pharmacological research
3. Inhibitors
Acetylisoeugenol
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock |
10 mM * 1 mL in DMSO / $8.9 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Am J Chin Med.2016, 44(8):1719-1735Molecules.2017, 22(11)Appl. Sci.2022, 12(17), 8646.Environ Toxicol.2021, doi: 10.1002Biorxiv2019, 10.1101Industrial Crops and Products...2018...Plant Growth Regulation...2020...Journal of Phytopathology...2021...
Sci Rep.2021, 11(1):21038.Phytochemistry Letters2017, 449-455Aquaculture2017, 481:94-102Processes2022, 10(10), 2008.Planta Med.2018, 84(6-07):465-474Oxid Med Cell Longev2020, 12Applied Physics B2021, 127(92).J of Apicultural Research2020, 10.1080
Mediators Inflamm.2016, 2016:7216912Int J Mol Sci.2019, 20(14):E3538J Cell Mol Med.2021, 25(5):2645-2654. Academic J of Second Military Med...2018...Molecules.2021, 26(3):695. Industrial Crops and Products...2022...Int J Mol Sci.2020, 21(19):7209.
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Our products had been exported to the following research institutions and universities, And still growing.
Gyeongsang National University (Korea)Srinakharinwirot University (Thailand)Lodz University of Technology (Poland)University of Zurich (Switzerland)
University of Queensland (Australia)University of East Anglia (United Kingdom)Deutsches Krebsforschungszentrum (Germany)Medizinische Universit?t Wien (Austria)
Auburn University (USA)Johannes Gutenberg University M... (Germany)Kazusa DNA Research Institute (Japan)
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Acetylisoeugenol
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Plant Physiol Biochem.2021, 160:166-174.Cardiovasc Toxicol.2021, 21(11):947-963.Plants (Basel).2021, 10(7):1376.Appl. Sci.2021, 11(24),12080J. Pharm. Res. Int.2022, 34(58): pp.1-14.Fitoterapia.2022, 157:105130.Cell Rep.2022, 39(1):110643. Antioxidants (Basel).2022, 11(10):1929. Industrial Crops and Products2017, 95:286-295Cancer Manag Res.2019, 11:483-500
Related Screening Libraries
Description: |
Acetylisoeugenol is a mild sensitizer in vivo, it shows good antifungal activities against R. solani and F. oxysporum. |
Targets: |
Antifection |
In vitro: |
Industrial Crops & Products, 2017, 97:388-394. | Structure-activity relationships of cinnamaldehyde and eugenol derivatives against plant pathogenic fungi.[Reference: WebLink] | METHODS AND RESULTS: Cinnamon bark oil showed a lower activity than clove bud oil. The fungicidal activity of cinnamaldehyde (IC50 = 75.4 and 156.9 μg/mL, respectively) and eugenol (IC50 = 58.9 and 52.9 μg/mL, respectively) against R. solani and F. oxysporum was also evalutated. Comparisons of the antifungal activities of cinnamaldehyde and eugenol derivatives revealed that α-methylcinnamaldehyde, α-methylcinnamic acid, methyleugenol, acetyleugenol, isoeugenol, methylisoeugenol, and Acetylisoeugenol showed good antifungal activities against R. solani and F. oxysporum. In structure-activity relationships, the fungicidal activity of cinnamaldehyde derivatives could be related to conjugated double bond and the length of CH chain outside the ring. In addition, the presence of the lipophilicity may have a considerable influence on the toxicity of phenylpropenes. CONCLUSIONS: The present approach may help future work in the search for fungicidal compounds. |
|
In vivo: |
J Dermatol. 1985 Apr;12(2):153-60. | Factors influencing conjugation of phenolic compounds with the epsilon-amino group.[Reference: WebLink] | METHODS AND RESULTS: Factors influencing the conjugation potency of eugenol (E), isoeugenol (IE), methyl isoeugenol (MIE), and Acetylisoeugenol (AIE) with [l-14C]07-aminocaproic acid are investigated. The conjugation reaction for IE is accelerated in the presence of H2O2-peroxidase and inhibited under anaerobic conditions by nitrogen gas flow. An oxidation reaction is found to be necessary for the conjugation of IE with 07-aminocaproic acid. Immediately after mixing the phenolic compounds with [1-14C]07-aminocaproic acid and H2O2-peroxidase, the main conjugates are 7.7% for IE, 2.1% for E, 0.7% for AIE, and 0.2% for MIE. IE, which is a potent sensitizer in vivo, produces the greatest amount of conjugates while MIE, which is negative in vivo, produces almost no conjugates. CONCLUSIONS: AIE and E, both mild sensitizers in vivo, produce less conjugates than IE. |
|
Acetylisoeugenol Description
Source: |
From Cinnamon bark oil. |
Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
1 mM |
4.8487 mL |
24.2436 mL |
48.4872 mL |
96.9744 mL |
121.218 mL |
5 mM |
0.9697 mL |
4.8487 mL |
9.6974 mL |
19.3949 mL |
24.2436 mL |
10 mM |
0.4849 mL |
2.4244 mL |
4.8487 mL |
9.6974 mL |
12.1218 mL |
50 mM |
0.097 mL |
0.4849 mL |
0.9697 mL |
1.9395 mL |
2.4244 mL |
100 mM |
0.0485 mL |
0.2424 mL |
0.4849 mL |
0.9697 mL |
1.2122 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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