ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $268 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Exp Parasitol.2017, 183:160-166PLoS One.2018, 13(3):e0193386Inflammation.2015, 38(4):1502-16Int J Mol Sci.2021, 22(16):8641.Korean Herb. Med. Inf. 2016, 4(1):35-42In Vivo.2022, 36(3):1136-1143. Food Chem.2019, 275:746-753African J. Agricultural Research ...2017...
Journal of Functional Foods...2017...Molecules2021, 26(1),230J Agric Food Chem....2021...Biochem Biophys Res Commun....2020...J Drug Delivery Science and Tech....2022...Antioxidants (Basel)....2022...Russian J Bioorganic Chemistry ...2021...Current Pharmaceutical Analysis...2017...
J Pharmacol Sci.2021, 147(2):184-191.J-STAGE2015, 249-255Dicle Tip Dergisi2020, 47(2),423-430.Nutrients.2019, 11(4):E936Planta Med.2019, 85(4):347-355Food Chem.2019, 290:286-294J Nat Med.2017, 71(2):457-462
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Our products had been exported to the following research institutions and universities, And still growing.
Kitasato University (Japan)Mahatma Gandhi University (India)Korea Institute of Oriental Med... (Korea)Kyung Hee University (Korea)
Yale University (USA)Sapienza University of Rome (Italy)Chungnam National University (Korea)University of Vigo (Spain)
Univerzita Karlova v Praze (Czech Republic)Utah State University (USA)Chiang Mai University (Thailand)
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Ajugasterone C
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
SBRAS2016, 12Evid Based Complement Alternat Med.2016, 2016:1739760J of Engineering Science&Technology2018, 13(9):2820-2828Evid Based Complement Alternat Med.2018, 2018:8565132Cosmetics2021, 8(3),91.Biochem Biophys Res Commun.2019, 518(4):732-738J Med Food.2019, 22(10):1067-1077J Food Sci.2022, 87(11):4905-4916.Chemistry of Plant Raw Materials2019, 4:135-147Institut Pasteur Korea2020, doi: 10.21203.
Related Screening Libraries
| Description: |
Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats. |
| Targets: |
Immunology & Inflammation related |
| In vivo: |
| Planta Med. 2013 Jan;79(1):52-9. | | Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects.[Pubmed: 23150078 ] | With reference to the ethnopharmacological significance of Vitex doniana Sweet (Lamiaceae) leaves in the treatment of stomach and rheumatic pains as well as inflammatory disorders, biological studies on its stem bark extracts have also reported anti-inflammatory and analgesic activities, with no attempt to identify the active components.
METHODS AND RESULTS:
Chromatographic and spectroscopic procedures identified three new phytoecdysteroids: 21-hydroxyshidasterone (1), 11β-hydroxy-20-deoxyshidasterone (2), and 2,3-acetonide-24-hydroxyecdysone (3) from the stem bark methanol extracts along with known ecdysteroids shidasterone (4), Ajugasterone C (5), 24-hydroxyecdysone (6), and 11β,24-hydroxyecdysone (7). The compounds (1-7) showed significant (p ≤ 0.05) inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats.
CONCLUSIONS:
These results suggest a possible contribution of ecdysteroids to the anti-inflammatory effect of some V. doniana stem bark extracts. |
|
Ajugasterone C Description
| Source: |
The herbs of Ajuga ciliata Bunge. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.0806 mL |
10.4028 mL |
20.8056 mL |
41.6112 mL |
52.014 mL |
| 5 mM |
0.4161 mL |
2.0806 mL |
4.1611 mL |
8.3222 mL |
10.4028 mL |
| 10 mM |
0.2081 mL |
1.0403 mL |
2.0806 mL |
4.1611 mL |
5.2014 mL |
| 50 mM |
0.0416 mL |
0.2081 mL |
0.4161 mL |
0.8322 mL |
1.0403 mL |
| 100 mM |
0.0208 mL |
0.104 mL |
0.2081 mL |
0.4161 mL |
0.5201 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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