Ajugasterone C | CAS:23044-80-6 | Manufacturer ChemFaces

Ajugasterone C

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Size /Price /Stock	10 mM * 1 mL in DMSO / $218 / In-stock
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Description:

Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats.

Targets:

Immunology & Inflammation related

In vivo:

Planta Med. 2013 Jan;79(1):52-9.

Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects.[Pubmed: 23150078 ]

With reference to the ethnopharmacological significance of Vitex doniana Sweet (Lamiaceae) leaves in the treatment of stomach and rheumatic pains as well as inflammatory disorders, biological studies on its stem bark extracts have also reported anti-inflammatory and analgesic activities, with no attempt to identify the active components.
METHODS AND RESULTS:
Chromatographic and spectroscopic procedures identified three new phytoecdysteroids: 21-hydroxyshidasterone (1), 11β-hydroxy-20-deoxyshidasterone (2), and 2,3-acetonide-24-hydroxyecdysone (3) from the stem bark methanol extracts along with known ecdysteroids shidasterone (4), Ajugasterone C (5), 24-hydroxyecdysone (6), and 11β,24-hydroxyecdysone (7). The compounds (1-7) showed significant (p ≤ 0.05) inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats.
CONCLUSIONS:
These results suggest a possible contribution of ecdysteroids to the anti-inflammatory effect of some V. doniana stem bark extracts.

Ajugasterone C Description

Source:	The herbs of Ajuga ciliata Bunge.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Ajugasterone C
Price:	$268 / 5mg
CAS No.:	23044-80-6
Catalog No.:	CFN90616
Molecular Formula:	C₂₇H₄₄O₇
Molecular Weight:	480.64 g/mol
Purity:	>=98%
Type of Compound:	Steroids
Physical Desc.:	Powder
Source:	The herbs of Ajuga ciliata Bunge.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-inflammatory Compound Library Steroids Compound Library Immunology & Inflammation related Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.0806 mL	10.4028 mL	20.8056 mL	41.6112 mL	52.014 mL
5 mM	0.4161 mL	2.0806 mL	4.1611 mL	8.3222 mL	10.4028 mL
10 mM	0.2081 mL	1.0403 mL	2.0806 mL	4.1611 mL	5.2014 mL
50 mM	0.0416 mL	0.2081 mL	0.4161 mL	0.8322 mL	1.0403 mL
100 mM	0.0208 mL	0.104 mL	0.2081 mL	0.4161 mL	0.5201 mL

CFN90611	4-Beta-Hydroxycholesterol	17320-10-4	402.66	C₂₇H₄₆O₂
CFN90610	7Beta-Hydroxycholesterol	566-27-8	402.65	C₂₇H₄₆O₂
CFN91812	7-Ketocholesterol	566-28-9	400.6	C₂₇H₄₄O₂
CFN91647	7-Oxocholesteryl acetate	809-51-8	442.7	C₂₉H₄₆O₃
CFN90609	27-Hydroxycholesterol	20380-11-4	402.65	C₂₇H₄₆O₂
CFN91582	Cholest-4,6-diene-3-ol	14214-69-8	384.6	C₂₇H₄₄O
CFN99419	Ponasterone A	13408-56-5	464.6	C₂₇H₄₄O₆
CFN90616	Ajugasterone C	23044-80-6	480.64	C₂₇H₄₄O₇
CFN92515	Inokosterone	15130-85-5	480.6	C₂₇H₄₄O₇
CFN93571	25S-Inokosterone	19595-18-7	480.6	C₂₇H₄₄O₇