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    Ajugasterone C
    Information
    CAS No. 23044-80-6 Price $268 / 5mg
    Catalog No.CFN90616Purity>=98%
    Molecular Weight480.64Type of CompoundSteroids
    FormulaC27H44O7Physical DescriptionPowder
    Download COA    MSDS    SDF    ManualSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $268 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Ajugasterone C

    Ajugasterone C
    Product Name Ajugasterone C
    CAS No.: 23044-80-6
    Catalog No.: CFN90616
    Molecular Formula: C27H44O7
    Molecular Weight: 480.64 g/mol
    Purity: >=98%
    Type of Compound: Steroids
    Physical Desc.: Powder
    Targets: Immunology & Inflammation related
    Source: The herbs of Ajuga ciliata Bunge.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $268 / 5mg
    Download: COA    MSDS    SDF    Manual
    Similar structural: Comparison (Web)  (SDF)
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
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  • Anti-inflammatory Compound Library
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  • Biological Activity
    Description: Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats.
    Targets: Immunology & Inflammation related
    In vivo:
    Planta Med. 2013 Jan;79(1):52-9.
    Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects.[Pubmed: 23150078 ]
    With reference to the ethnopharmacological significance of Vitex doniana Sweet (Lamiaceae) leaves in the treatment of stomach and rheumatic pains as well as inflammatory disorders, biological studies on its stem bark extracts have also reported anti-inflammatory and analgesic activities, with no attempt to identify the active components.
    METHODS AND RESULTS:
    Chromatographic and spectroscopic procedures identified three new phytoecdysteroids: 21-hydroxyshidasterone (1), 11β-hydroxy-20-deoxyshidasterone (2), and 2,3-acetonide-24-hydroxyecdysone (3) from the stem bark methanol extracts along with known ecdysteroids shidasterone (4), Ajugasterone C (5), 24-hydroxyecdysone (6), and 11β,24-hydroxyecdysone (7). The compounds (1-7) showed significant (p ≤ 0.05) inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats.
    CONCLUSIONS:
    These results suggest a possible contribution of ecdysteroids to the anti-inflammatory effect of some V. doniana stem bark extracts.
    Ajugasterone C Description
    Source: The herbs of Ajuga ciliata Bunge.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0806 mL 10.4028 mL 20.8056 mL 41.6112 mL 52.014 mL
    5 mM 0.4161 mL 2.0806 mL 4.1611 mL 8.3222 mL 10.4028 mL
    10 mM 0.2081 mL 1.0403 mL 2.0806 mL 4.1611 mL 5.2014 mL
    50 mM 0.0416 mL 0.2081 mL 0.4161 mL 0.8322 mL 1.0403 mL
    100 mM 0.0208 mL 0.104 mL 0.2081 mL 0.4161 mL 0.5201 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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