ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $229.0 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Br J Pharmacol.2016, 173(2):396-410J Ethnopharmacol.2017, 198:205-213Sci Rep.2017, 7(1):3249Food Res Int.2017, 96:40-45J Cell Mol Med.2018, 22(9):4236-4242Bioorg Med Chem.2018, 26(14):4201-4208Phytomedicine.2018, 41:62-66Sci Rep.2018, 8:15059
Biorxiv2019, 10.1101Exp Biol Med (Maywood)....2019...Chemistry of Plant Raw Materials...2019...J of Ana. Chem.2019, 74(11):1113-1121Biomed Chromatogr.2019, 8:e4774Saudi Pharm J2020, 10.1016Nutrients2020, 12(3):811.Drug Des Devel Ther.2020, 14:969-976.
Biochem Pharmacol.2020, 178:114083Oncol Lett.2020, 20(4):122.J Cell Mol Med....2020...Molecules.2020, 25(18):4283.J Biomed Sci.2020, 27(1):60.Bioorg Med Chem.2020, 28(12):115553.Korean J Dent Mater2020, 47(2):63-70.
Our products had been exported to the following research institutions and universities, And still growing.
Stanford University (USA)Gyeongsang National University (Korea)Universidade Federal de Pernamb... (Brazil)University of Mysore (India)
VIB Department of Plant Systems... (Belgium)Sant Gadge Baba Amravati Univer... (India)Aveiro University (Portugal)University of Queensland (Australia)
National Hellenic Research Foun... (Greece)University of Malaya (Malaysia)Chinese University of Hong Kong (China)
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Curr Top Med Chem.2020, 20(21):1898-1909.Nutrients.2018, 10(7)Industrial Crops and Products2019, 140:111612Nutrients.2019, 12(1):E40J Cell Mol Med.2020, 24(21):12308-12317.J Sep Sci.2019, 42(21):3352-3362Molecules.2019, 24(24):E4536Research on Crops.2017, 18(3):569Biosci Rep.2020, 40(8):BSR20201219.Plos One.2019, 15(2):e0220084
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Phenols Compound Library
|| Pieceid-2''-O-gallate has antioxidant activity.|
|Phytochemistry, 2003, 64(3):759-763. |
|Stilbenes from the roots of Pleuropterus ciliinervis and their antioxidant activities.[Reference: WebLink]|
METHODS AND RESULTS:
Two stilbene glycosides, Pieceid-2''-O-gallate and pieceid-2″-O-coumarate, were isolated from the MeOH extract of the roots of Pleuropterus ciliinervis Nakai (Polygonaceae), together with two known compounds, resveratrol and pieceid. Their structures were determined spectroscopically, particularly by 2D NMR spectroscopic analysis. The antioxidant activities of stilbenes isolated were determined in vitro against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, superoxide radicals and by determining their lipid peroxidation inhibitory activities. Among the compounds isolated, pieceid-2″-O-gallate had the most potent inhibitory scavenging effect on DPPH, superoxide radicals and upon lipid peroxidation inhibition with IC50 values of 16.5, 23.9 and 5.1 μM, respectively.
Two stilbene glycisides, (E)-pieceid-2″-O-gallate and (E)-pieceid 2″-O-cumarate, were isolated from the roots of P. ciliinervis, together with resveratrol and pieceid. They showed antioxidant activities.
||The roots of Pleuropterus ciliinervis
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Química Nova,2014, 37(9):1465-1468. |
|Separation and purification of three stilbenes from the radix of Polygonum cillinerve (Nakai) Ohwl by macroporous resin column chromatography combined with high-speed counter-current chromatography.[Reference: WebLink]|
|Recebido em 26/03/2014; aceito em 08/07/2014; publicado na web em 22/09/2014 An effective method for the rapid separation and purification of three stilbenes from the radix of Polygonum cillinerve (Nakai) Ohwl by macroporous resin column chromatography combined with high-speed counter-current chromatography (HSCCC) was successfully established.
METHODS AND RESULTS:
In the present study, a two-phase solvent system composed of chloroform-n-butanol-methanol-water (4:1:4:2, v/v/v/v) was used for HSCCC separation. A one-step separation in 4 h from 150 mg of crude extract produced 26.3 mg of trans-resveratrol-3-O-glucoside, 42.0 mg of Pieceid-2''-O-gallate, and 17.9 mg of trans-resveratrol with purities of 99.1%, 97.8%, and 99.4%, respectively, as determined by high-performance liquid chromatography (HPLC).
The chemical structures of these compounds were identified by nuclear magnetic resonance (NMR) spectroscopy.