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    Natural Products
    Apohyoscine
    Apohyoscine
    Information
    CAS No. 535-26-2 Price
    Catalog No.CFN00150Purity>=98%
    Molecular Weight285.34Type of CompoundAlkaloids
    FormulaC17H19NO3Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Apohyoscine

    Apohyoscine
    Product Name Apohyoscine
    CAS No.: 535-26-2
    Catalog No.: CFN00150
    Molecular Formula: C17H19NO3
    Molecular Weight: 285.34 g/mol
    Purity: >=98%
    Type of Compound: Alkaloids
    Physical Desc.: Powder
    Source: The aerial parts of Datura innoxia.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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    Description: Reference standards.
    Apohyoscine Description
    Source: The aerial parts of Datura innoxia.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.5046 mL 17.523 mL 35.0459 mL 70.0918 mL 87.6148 mL
    5 mM 0.7009 mL 3.5046 mL 7.0092 mL 14.0184 mL 17.523 mL
    10 mM 0.3505 mL 1.7523 mL 3.5046 mL 7.0092 mL 8.7615 mL
    50 mM 0.0701 mL 0.3505 mL 0.7009 mL 1.4018 mL 1.7523 mL
    100 mM 0.035 mL 0.1752 mL 0.3505 mL 0.7009 mL 0.8761 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Planta Medica, 1980,38(4):356-358.
    Metabolism of hyoscine fed to the aerial parts of Solandra grandiflora.[Reference: WebLink]

    METHODS AND RESULTS:
    (-)-Hyoscine infiltrated into the aerial parts of S. grandiflora was transformed to ( plus or minus )-hyoscine, Apohyoscine, ( plus or minus )-norhyoscine, scopine and oscine.
    Phytochemistry,1976,15(2): 287-9.
    Biosynthesis of C6-C3 acids in Datura innoxia[Reference: WebLink]

    METHODS AND RESULTS:
    Datura innoxia plants were fed via the roots with cinnamic acid-[214C], (±)-phenyllactic (2-hydroxy-3-phenylpropanoic) acid-[214C] and phenylalanine-[2-14C]. In each case Apohyoscine, hyoscine, hyoscyamine and littorine were isolated from the aerial parts, and hyoscine, hyoscyamine and littorine from the roots. Cinnamic acid was not incorporated into the acid moieties of the alkaloids. Phenyllactic acid served as a better precursor than phenylalanine for tropic acid (hyoscine and hyoscyamine) and atropic acid (Apohyoscine).
    CONCLUSIONS:
    Phenylalanine served as an effective precursor for the phenyllactic acid moiety of Littorine.
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