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1. Reference standards
2. Pharmacological research
3. Inhibitors
Violanone
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $175.7 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
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Violanone
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Molecules2022, 27(9):2827.Processes2021, 9(11),2065.Molecules.2019, 24(1):E159Preprints2022, 2022030063.Biomimetics (Basel).2022, 7(4):154. Onco Targets Ther.2017, 10:3467-3474Journal of Functional Foods2021, 84:104581Chemistry of Natural Compounds2018, 54(3):572-576Front Cell Infect Microbiol.2018, 8:292Natural Product Res.&Deve.2022, 1001-6880.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
Violanone, an isoflavanone compound, can inhibit tubulin polymerization. Violanone also exhibits larvicidal activity against A. aegypti. |
| In vitro: |
| Exp Parasitol . 2015 Jun;153:160-164. | | Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito[Pubmed: 25819294] | | The larvicidal activities of extracts of three hardwood species (Hymenaea stigonorcapa, Anadenanthera colubrina and Bowdichia virgilioides) against 4th instar larvae of Aedes aegypti were evaluated using WHO guidelines. Extracts of H. stignocarpa and A. colubrina showed weak activity. The highest larvicidal effect was obtained with the cyclohexane extract of the heartwood of B. virgilioides, which caused 100% mortality at concentrations at 50 and 100 μg/mL. Fraction toluene/EtOAc (8:2) from this extract showed larvicidal activity (LC₅₀ = 34.90 ± 1.27 μg/mL). A mixture of two compounds identified as medicarpin and maackiain exhibited a very good larvicidal activity (sub-fraction 2, LC₅₀ = 17.5 ± 1.87 μg/mL) and maackiain showed to be a strong larvicidal compound (LC₅₀ = 21.95 ± 1.34 μg/mL). This result can be of value in the search for new natural larvicidal compounds from other hardwood plant extracts and presents the first report of B. virgilioides being used to control a mosquito vector. | | Tetrahedron. 2007 Dec 24; 63(52): 12986-12993. | | Synthesis and biological evaluation of isoflavone analogues from Dalbergia oliveri[Reference: WebLink] | | Mucronulatol 1 and Violanone 2 isolated from Dalbergia oliveri Gamble, and the corresponding isoflavone 3 were prepared by ligand coupling reactions involving organolead reagent. Biological studies have shown a significant cytotoxic effect against an HBL100 leukemia cell line only for isoflavan 1 with an IC50 value amounting to 5.7 μM. All the drugs modestly inhibit the in vitro microtubule assembly, independently of the cytotoxic ability. Natural compounds 1 and 2 have no antibacterial activity, but are potent inhibitors of the Fusarium oxysporum phytopathogenic fungal growth. |
|
Violanone Description
| Source: |
The roots of Parochetus communis |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.1616 mL |
15.8078 mL |
31.6156 mL |
63.2311 mL |
79.0389 mL |
| 5 mM |
0.6323 mL |
3.1616 mL |
6.3231 mL |
12.6462 mL |
15.8078 mL |
| 10 mM |
0.3162 mL |
1.5808 mL |
3.1616 mL |
6.3231 mL |
7.9039 mL |
| 50 mM |
0.0632 mL |
0.3162 mL |
0.6323 mL |
1.2646 mL |
1.5808 mL |
| 100 mM |
0.0316 mL |
0.1581 mL |
0.3162 mL |
0.6323 mL |
0.7904 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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