ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $318 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Phytomedicine.2015, 22(4):498-503Food Science and Biotechnology...2015...J Agric Food Chem.2015, 63(44):9869-78Korean J. of Food Sci. and Tech...2016...Polytechnic University of Catalon...2017...Universidade Estadual Paulista...2017...Research on Crops.2017, 18(3):569Int J Mol Sci.2017, 18(5)
J Ethnopharmacol.2017, 197:157-164Molecules.2017, 22(3)Korean J of Food Science&Technolo...2017...J of the Korean Society of Cosmet...2018...Oncology Letters2018, 4690-4696Int J Mol Sci.2019, 20(21):E5488Chemistry of Natural Compounds...2019...Br J Pharmacol.2020, 10.1111
United States Patent Application...2020...Appl. Sci.2020, 10(5),1713.LWT2020, 130:109535Molecules.2020, 25(7):1625.Bioorg Med Chem.2020, 28(12):115553.Exp Mol Med.2020, 52(4):629-642.SCOPUS.2020, 836-847.
Our products had been exported to the following research institutions and universities, And still growing.
University of Melbourne (Australia)Chiang Mai University (Thailand)Harvard University (USA)Northeast Normal University Cha... (China)
Utrecht University (Netherlands)Uniwersytet Medyczny w ?odzi (Poland)University of Leipzig (Germany)Ateneo de Manila University (Philippines)
Centrum Menselijke Erfelijkheid (Belgium)Monash University (Australia)Max Rubner-Institut (MRI) (Germany)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Plant Growth Regulation2020, 90(2):383-392Int J Mol Sci.2019, 20(21):E5488Food Chem.2019, 275:746-753Asian Journal of Chemistry2014, 26(22):7811-7816Molecules.2017, 22(6)Anticancer Res.2014, 34(7):3505-9Invest New Drugs.2017, 35(2):166-179J Chromatogr A.2017, 1518:46-58Oncotarget.2017, 8(53):90925-90947Korean Herb. Med. Inf.2020, 8(2):243-254.
Related Screening Libraries
||Arjunic acid is a strong antioxidant and a free radical scavenger.
Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL. |
||Antifection | COX|
|Am J Chin Med. 2008;36(1):197-207. |
|Arjunic acid, a strong free radical scavenger from Terminalia arjuna.[Pubmed: 18306462]|
|This study was designed to investigate the antioxidant and free radical scavenging capacities of Arjunic acid, an aglycone obtained from the fruit of medicine Terminalia Fruit. |
METHODS AND RESULTS:
Liver microsomes, mitochondria, and red blood cells (RBCs) were prepared from Wistar rats. The antioxidant capacity was determined by the inhibitory effect on lipid peroxidation, hydrogen peroxide induced RBCs hemolysis, and RBCs autoxidative hemolysis. The free radical scavenging activity was tested by DPPH method and 2',7'-dichlorodihydrofluoresc in diacetate (DCFH(2)-DA) assay. Ascorbic acid was chosen as the positive controls. Results showed that Arjunic acid was a strong antioxidant and a free radical scavenger, more potent than ascorbic acid, in microsomes lipid peroxidation, DPPH, hydrogen peroxide induced RBCs hemolysis, and (DCFH(2)-DA) assay (p < 0.05). However, no significant difference was observed in the RBCs autoxidative hemolysis assay (p > 0.05).
|Planta Med. 2008 Mar;74(4):411-3. |
|Isolation and biological activities of termilignan B and arjunic acid from Terminalia sericea roots.[Pubmed: 18484533]|
|Bioassay-guided fractionation of ethyl acetate root extracts of Terminalia sericea yielded a new compound, termilignan B, and the known Arjunic acid. |
METHODS AND RESULTS:
Both compounds showed activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL. The lowest MIC value (1.9 microg/mL) was observed with termilignan B against Bacillus subtilis. Neither of the compounds showed significant activity against Mycobacterium aurum A+. In the cyclooxygenase assays, the compounds showed weak inhibitory activity with IC (50) values of 78 microM (COX-1) and 156 microM (COX-2) (termilignan B) and 36 microM (COX-1) and 253 microM (COX-2) (Arjunic acid). No potential mutagenic effects were observed with the two compounds in the Salmonella microsome assay (TA 98).
Arjunic acid Description
||The stem barks of Terminalia arjuna
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.