ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
3. Inhibitors
Asiaticoside B
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $102.7 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Universidade Estadual Paulista...2017...Biomed Pharmacother.2021, 137:111362.Antioxidants (Basel).2021, 10(8):1300. Appl. Sci.2020, 10,1304J Cell Physiol.2021, 236(3):1950-1966.Acta Chromatographica2021, 00960.Academic J of Second Military Med...2018...Inflammation.2021, doi: 10.1007
LWT2021, 147:111620.Exp Neurobiol.2018, 27(3):200-209J Chromatogr B Analyt Technol Bio...2019...Environ Toxicol.2019, 34(4):513-520.Pharmacol Rep.2022, 74(1):175-188.Arch Biochem Biophys.2020, 687:108363.VNU Journal of Science: Med.& Pha...2022...Curr Issues Mol Biol....2022...
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Our products had been exported to the following research institutions and universities, And still growing.
Subang Jaya Medical Centre (Malaysia)FORTH-IMBB (Greece)Srinakharinwirot University (Thailand)Monash University (Australia)
University of Eastern Finland (Finland)Regional Crop Research Institute (Korea)University of Indonesia (Indonesia)University of Toronto (Canada)
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Asiaticoside B
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J Phys Chem Lett.2021, 12(7):1793-1802.Chem Biol Interact.2018, 283:59-74Korean Herb. Med. Inf.2020, 8(2):233-242. Evid Based Complement Alternat Med.2020, 2020:9416962.Sci Rep.2021, 11(1):14180. Int J Mol Sci.2022, 23(21):13406.J Appl Biol Chem.2021, 64(3),263?268PLoS One.2018, 13(3):e0193386J of the Society of Cosmetic Scientists of Korea2018, 44(4):407-417Pak J Pharm Sci.2019, 32(6)
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Triterpenoids Compound Library |
| Description: |
Asiaticoside B has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines. |
| In vitro: |
| J Nat Prod. 2006 Oct;69(10):1500-2. | | Cytotoxic cycloartane triterpene saponins from Actaea asiatica.[Pubmed: 17067171 ] |
METHODS AND RESULTS:
Three new 9,19-cycloartane triterpene glycosides, asiaticoside A (1), Asiaticoside B (2), and 25-O-ethylcimigenol-3-O-beta-D-xylopyranoside (3), together with cimiacemoside I (4), 25-O-acetylcimigenol-3-beta-O-D-xyloside (5), and 25-anhydrocimigenol-beta-O-D-xyloside (6) were isolated from the roots/rhizomes extract of Actaea asiatica, and their structures were established by spectroscopic methods (IR, HRESIMS, and NMR).
CONCLUSIONS:
Compounds 1-3, 5, and 6 had notable cytotoxicity against HepG2 and MCF-7 cancer cell lines. |
|
Asiaticoside B Description
| Source: |
The herbs of Centella asiatica (L.) Urban |
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.0255 mL |
5.1275 mL |
10.255 mL |
20.5101 mL |
25.6376 mL |
| 5 mM |
0.2051 mL |
1.0255 mL |
2.051 mL |
4.102 mL |
5.1275 mL |
| 10 mM |
0.1026 mL |
0.5128 mL |
1.0255 mL |
2.051 mL |
2.5638 mL |
| 50 mM |
0.0205 mL |
0.1026 mL |
0.2051 mL |
0.4102 mL |
0.5128 mL |
| 100 mM |
0.0103 mL |
0.0513 mL |
0.1026 mL |
0.2051 mL |
0.2564 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Pharmazie. 2003 Jun;58(6):381-4. | | An improved HPLC method for quantitative determination of six triterpenes in Centella asiatica extracts and commercial products.[Pubmed: 12856998] |
METHODS AND RESULTS:
An improved HPLC qualitative and quantitative method of six triterpenes (asiaticoside, madecassoside, asiatic acid, madecassic acid, terminolic acid, and Asiaticoside B) in Centella asiatica (raw plant material and preparations) is described in this paper. After 50 minutes the six active triterpenes were separated and detected in the methanolic extract at a limit of 0.01 microg/ml.
CONCLUSIONS:
The method uses a Phenomenex Aqua 5mu C18 (200 A) column as the stationary phase, a gradient mobile phase of water (0.1% TFA), acetonitrile (0.1% TFA), and methyl tert-butyl ether (0.1% TFA), and UV detection at 206 nm. The correlation coefficients for the calibration curves and the recovery rates ranged from 0.995 to 0.999 and from 98.39% to 100.02%, respectively. The qualitative and quantitative results are discussed. |
|
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