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1. Reference standards
2. Pharmacological research
3. Inhibitors
Caesalpin J
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Front Aging Neurosci.2019, 11:230Nutrients.2019, 11(6):E1380Free Radic Biol Med.2016, 97:307-319Sci Rep.2018, 8(1):12970Bioorg Med Chem.2020, 28(12):115553.Chemistry of plant raw materials...2021...Antioxidants (Basel).2020, 9(6):544. Pak J Pharm Sci.2018, 31:311-315
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Caesalpin J
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Mol Neurobiol.2022, 02873-9.Mol Plant Pathol.2022, 10.1111:mpp.13280.J Sep Sci.2018, 41(9):1938-1946Mediators Inflamm.2016, 2016:7216912Biomedicine & Pharmacotherapy2022, 153:113404.Drug Chem Toxicol.2020, 1-14. Plants (Basel).2020, 9(11):1535.J Ethnopharmacol.2019, 228:132-141LWT2021, 150:112021.Pak J Pharm Sci.2018, 31:311-315
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
Reference standards. |
| In vitro: |
| Arch Pharm Res. 2003 Feb;26(2):147-50. | | A DNA strand-nicking principle of a higher plant, Caesalpinia sappan.[Pubmed: 12643592 ] |
METHODS AND RESULTS:
To find anticancer agents from higher plants, DNA strand-scission assay method was employed for bioassay-guided fractionation as well as for screening the crude extracts. During the screening, an ethyl acetate extracts of the heartwood of Caesalpinia sappan L. (Leguminosae) exhibited potent DNA strand-scission activity.
CONCLUSIONS:
Therefore, the ethyl acetate extracts of the dried heartwood of C. sappan was subjected to the bioassay-guided fractionation, which led to the isolation of a known compound, brazilin (1) as the active constituent. In addition, caesalpine J (2) was also isolated as an inactive constituent. |
|
Caesalpin J Description
| Source: |
The herbs of Caesalpinia decapetala |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.1616 mL |
15.8078 mL |
31.6156 mL |
63.2311 mL |
79.0389 mL |
| 5 mM |
0.6323 mL |
3.1616 mL |
6.3231 mL |
12.6462 mL |
15.8078 mL |
| 10 mM |
0.3162 mL |
1.5808 mL |
3.1616 mL |
6.3231 mL |
7.9039 mL |
| 50 mM |
0.0632 mL |
0.3162 mL |
0.6323 mL |
1.2646 mL |
1.5808 mL |
| 100 mM |
0.0316 mL |
0.1581 mL |
0.3162 mL |
0.6323 mL |
0.7904 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| J Asian Nat Prod Res. 2014;16(2):187-91. | | Two new degradative cassane-type diterpenes isolated from Caesalpinia minax.[Pubmed: 24325258 ] | Cassane-type diterpenes are main bioactive constituents of Caesalpinia minax HANCE.
METHODS AND RESULTS:
As a part of our ongoing chemical investigation of C. minax, two new degradative cassane-type diterpenes, named caesalpin I (1) and Caesalpin J (2), were isolated from the EtOAc extract of the seeds of C. minax. The structures were elucidated by means of spectroscopic analysis. |
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