ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
(+)-Carvone
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
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Contact Us
Order & Inquiry & Tech Support
Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery time
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $7.0 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Internoational J of Toxicology...2020...Plant Cell Physiol.2018, 59(1):128-141Chem Pharm Bull (Tokyo)....2019...Molecules.2017, 22(3)Chinese J of Tissue Engineering R...2022...J Agric Food Chem....2020...Chem Biol Interact.2019, 315:108910Front Pharmacol.2019, 10:1226
Food Chem.2020, 332:127412Nat Prod Commun.2017, 12(5):771-778Agronomy2022, 12(10), 2426.Int J Mol Sci.2021, 22(11):5503.PLoS One.2017, 12(3):e0173585Drug Dev Res.2022, 83(7):1673-1682. Evid Based Complement Alternat Me...2016...Nat Prod Sci.2014, 20(3):182-190
J of Applied Biological Chem....2020...Microchemical Journal2018, 137:168-173Molecules.2016, 21(10)J Inflamm Res.2022, 15:5347-5359.Eur J Pharm Sci.2016, 94:33-45J Nat Prod.2018, 81(4):966-975Phytomedicine.2022, 100:154036.
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Our products had been exported to the following research institutions and universities, And still growing.
University of Parma (Italy)Korea Food Research Institute(K... (Korea)Universiti Malaysia Pahang (Malaysia)Universidad de Antioquia (Colombia)
Florida International University (USA)The Australian National University (Australia)Institute of Tropical Disease U... (Indonesia)Michigan State University (USA)
Mendel University in Brno (Czech Republic)University of Leipzig (Germany)China Medical University (Taiwan)
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(+)-Carvone
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Foods.2022, 11(12):1708.Nutrients.2021, 13(3):978. Pharmaceuticals (Basel).2021, 14(10):1046.Front Pharmacol.2021, 12:690113.Biomed Pharmacother.2019, 116:108987The Catharanthus Genome2022,35-83.LWT2021, 138:110630.Vietnam Journal of Science2022,64(2):69-75.Phytomedicine.2018, 38:12-23Oncotarget.2015, 6(31):30831-49
Related Screening Libraries
| Description: |
(S)-(+)-Carvone appears to have anticonvulsant-like activity. |
| In vivo: |
| Chirality, 2010, 19(4):264-268. | | Influence of the chirality of (R)-(-)- and (S)-(+)-carvone in the central nervous system: a comparative study.[Pubmed: 17299731] | Many terpenes are used therapeutically, and as flavor and fragrance materials. (R)-(-)-Carvone, the main constituent of spearmint oil, and (S)-(+)-Carvone, found as major component of caraway and dill seed oils, have several applications and are used in cosmetic, food, and pharmaceutical preparations.
METHODS AND RESULTS:
In this study, the effect of enantiomers of carvone on the central nervous system (CNS) was evaluated in mice. The LD50 value was 484.2 mg/kg (358.9-653.2) for (S)-(+)-Carvone, and 426.6 (389.0-478.6) mg/kg for (R)-(-)-carvone. Both enantiomers caused depressant effects, such as decrease in the response to the touch and ambulation, increase in sedation, palpebral ptosis, and antinociceptive effects. (S)-(+)- and (R)-(-)-carvone caused a significant decrease in ambulation. (R)-(-)-Carvone appeared to be more effective than its corresponding enantiomer at 0.5 and 2.0 h after administration. However, (S)-(+)-Carvone was slightly more potent at 1 h. In potentiating pentobarbital sleeping time, (R)-(-)-carvone was more effective than (S)-(+)-Carvone at 100 mg/kg, but was less potent at 200 mg/kg compared to the (+)-enantiomer, indicating a sedative action. (S)-(+)-Carvone at the dose of 200 mg/kg increased significantly the latency of convulsions induced by PTZ and PIC, but (R)-(-)-carvone was not effective against these convulsions.
CONCLUSIONS:
These results suggest that (S)-(+)-Carvone and (R)-(-)-carvone have depressant effect in the CNS. (S)-(+)-Carvone appears to have anticonvulsant-like activity. |
|
(+)-Carvone Description
| Source: |
The seed oil of dill. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
6.6578 mL |
33.2889 mL |
66.5779 mL |
133.1558 mL |
166.4447 mL |
| 5 mM |
1.3316 mL |
6.6578 mL |
13.3156 mL |
26.6312 mL |
33.2889 mL |
| 10 mM |
0.6658 mL |
3.3289 mL |
6.6578 mL |
13.3156 mL |
16.6445 mL |
| 50 mM |
0.1332 mL |
0.6658 mL |
1.3316 mL |
2.6631 mL |
3.3289 mL |
| 100 mM |
0.0666 mL |
0.3329 mL |
0.6658 mL |
1.3316 mL |
1.6644 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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