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Clemaphenol A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Clemaphenol A
Price: $338 / 5mg
CAS No.: 362606-60-8
Catalog No.: CFN90952
Molecular Formula: C20H22O6
Molecular Weight: 358.39 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The whole plants of Cynanchum auriculatum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $227.8 / In-stock
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Clemaphenol A is a natural product from Cynanchum auriculatum.
Clemaphenol A Description
Source: The whole plants of Cynanchum auriculatum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7903 mL 13.9513 mL 27.9026 mL 55.8051 mL 69.7564 mL
5 mM 0.5581 mL 2.7903 mL 5.5805 mL 11.161 mL 13.9513 mL
10 mM 0.279 mL 1.3951 mL 2.7903 mL 5.5805 mL 6.9756 mL
50 mM 0.0558 mL 0.279 mL 0.5581 mL 1.1161 mL 1.3951 mL
100 mM 0.0279 mL 0.1395 mL 0.279 mL 0.5581 mL 0.6976 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhong Yao Cai. 2015 Nov;38(11):2318-20.
Chemical Constituents of Cynanchum auriculatum.[Pubmed: 27356383]
To study the chemical constituents of Cynanchum auriculatum.
METHODS AND RESULTS:
Nine compounds were isolated by silica gel, RP-18 column chromatography and Sephadex LH20. Nine compounds were isolated from the ethanol extract of Cynanchum auriculatum. Their structures were determined as sarcosin-3-O-β-cymaropyranoside (1), cynotophylloside B (2), Clemaphenol A (3), deacetylmetaplexigenin (4), methyl-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl- (1 --> 4) -6-deoxy-3-O-methyl-α-L-ribo-hexopyranoside (5), trans-p-hydroxy cinnamic methyl ester (6), cyclo(D-Pro-D-Leu) (7), 3α-hydroxy-5α ,6α-epoxy-7-megastigmen9-one (8) and ferulic acid methyl ester (9) on the basis of spectral analysis.
CONCLUSIONS:
Compounds 3, 5 and 6 - 9 are isolated from Cynanchum auriculatum for the first time.
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Fangchinoline

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Napellonine

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Brucine

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