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|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
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More articles cited ChemFaces products.
Plant Methods.2017, 13:108Mol Pharm.2017, 14(9):3164-3177Semyung University2017, 149407BMC Complement Altern Med....2017...Evid Based Complement Alternat Me...2017...JPC-Journal of Planar Chromatogra...2017...Invest New Drugs.2017, 35(2):166-179Int. J. of Food Properties...2017...
J Pharm Biomed Anal.2018, 151:32-41Cell.2018, 172(1-2):249-261Phytomedicine.2018, 38:12-23Eur J Pharmacol.2018, 832:96-103Planta Med.2018, 84(6-07):465-474Plant Physiol Biochem.2019, 144:355-364Journal of Apiculture...2019...Korean Journal of Pharmacognosy....2019...
Agronomy2020, 10(10),1489UDC.2020, 19(4).Molecules.2020, 25(23):5609. J Food Biochem.2020, 44(6):e13198. Applied Biological Chemistry...2020...Indian J. of Experimental Bio....2020...Front Plant Sci.2020，11:630.
Our products had been exported to the following research institutions and universities, And still growing.
University of Amsterdam (Netherlands)FORTH-IMBB (Greece)University of Maryland School o... (USA)University of Toronto (Canada)
University of Medicine and Phar... (Romania)Regional Crop Research Institute (Korea)Leibniz Institute of Plant Bioc... (Germany)Weizmann Institute of Science (Israel)
MTT Agrifood Research Finland (Finland)University of Hertfordshire (United Kingdom)University Medical Center Mainz (Germany)
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Molecules.2016, 21(10)Biochem Biophys Res Commun.2018, 505(4):1148-1153Research on Crops.2017, 18(3):569Nat Prod Communications2018, 10.1177J Vet Sci.2020, 21(3):e39.LWT2020, 130:109535Nutraceutical Research . 2021, 19(1),p90-105.J Breast Cancer.2015, 18(2):112-118J Ginseng Res.2020, 44(4):611-618.J Ethnopharmacol.2020, 260:112988.
Related Screening Libraries
|| Coronarin E exhibits weak antimicrobial activity.|
|Asian J. Pharm. Clin. Res., 2015, 8(5):221-6. |
|Chemical composition and antimicrobial activity of diterpene and essential oils of hedychium roxburghii blume rhizome[Reference: WebLink]|
| The objective of the present study was to isolate and determine diterpene compound and essential oils from Hedychium roxburghii Blume rhizome and investigated those antimicrobial activities. |
METHODS AND RESULTS:
The essential oils were obtained by steam distillation method, the residual was then extracted by reflux with ethanol. The content of essential oils was analyzed by gas chromatography-mass spectrometry (GC/MS) method. Ethanolic residual-distillation extract was concentrated then used to isolate compound 1 by vacuum liquid chromatography and centrifugal chromatography. It was characterized by infrared spectrophotometry, 1H-nuclear magnetic resonance (NMR), 13C-NMR, heteronuclear single quantum coherence-NMR, heteronuclear multiple bond correlation-NMR and carbon coupling 13C-NMR. The antimicrobial activity of essential oils, ethanolic residual-distillation extract and compound 1 were carried out by microdilution method. The oils exhibited antimicrobial activity against Bacillus subtilis American Type Culture Collection (ATCC) 6633 (minimum inhibitory concentration [MIC] 1750 μg/ml), Staphylococcus aureus ATCC 6538 (MIC 1750 μg/ml), Escherichia coli ATCC 8939 (MIC 3500 μg/ml), Pseudomonas aeruginosa ATCC 9027 (>3500 μg/ml) and Candida albicans ATCC 10231 (MIC 875 μg/ml). A phytochemical study of the rhizome essential oils of H. roxburghii Blume were performed by GC/MS and the result showed that fenchyl acetate (45.85%) was the main component of the oils. Compound 1 was identified as diterpene compound, Coronarin E. Coronarin E have not exhibited MIC at 512 μg/ml, however, it showed inhibition profile against all of tested microbes.
The essential oils and ethanolic residual-distillation extract of H. roxburghii Blume rhizome exhibited weak antimicrobial profile. Compound 1 was identified as diterpene compound, (Coronarin E), it was exhibited weak antimicrobial activity, but showed inhibition profile against all of the tested microbes.
Coronarin E Description
||The rhizomes of Hedychium coronarium
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Chem Pharm Bull (Tokyo). 2008 Mar;56(3):398-403. |
|Concise syntheses of coronarin A, coronarin E, austrochaparol and pacovatinin A.[Pubmed: 18310958]|
|Total syntheses of (+)-coronarin A (1), (+)-Coronarin E (2), (+)-austrochaparol (3) and (+)-pacovatinin A (4) were achieved from the synthetic (+)-albicanyl acetate (6).
METHODS AND RESULTS:
Dess-Martin oxidation of (+)-albicanol (5) derived from the chemoenzymatic product (6) gave an aldehyde (7), which was subjected to Julia one-pot olefination using beta-furylmethyl-heteroaromatic sulfones (8 or 9 ) gave (+)-trans Coronarin E (2) and (+)-cis Coronarin E (12) with high cis-selectivity. The synthesis of (+)-coronarin A (1) from (+)-trans Coronarin E (2) was achiev-ed, while (+)-cis Coronarin E (12) was converted to the natural products (+)-(5S,9S,10S)-15,16-epoxy-8(17),13(16),14-labdatriene (13) and (+)-austrochaparol (3).
By the asymmetric synthesis of (+)-3, the absolute structure of (+)-3 was determined to be 5S, 7R, 9R, 10S configurations. Homologation of (+)-albicanol (5) followed by allylic oxidation gave (7 alpha)-hydroxy nitrile (17), which was finally converted to the natural (+)-pacovatinin A (4) in 8 steps from (+)-albicanol (5).