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DL-Proline
DL-Proline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name DL-Proline
Price: $30 / 20mg
CAS No.: 609-36-9
Catalog No.: CFN70166
Molecular Formula: C5H9NO2
Molecular Weight: 115.1 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
DL-Proline Description
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 8.6881 mL 43.4405 mL 86.881 mL 173.7619 mL 217.2024 mL
5 mM 1.7376 mL 8.6881 mL 17.3762 mL 34.7524 mL 43.4405 mL
10 mM 0.8688 mL 4.344 mL 8.6881 mL 17.3762 mL 21.7202 mL
50 mM 0.1738 mL 0.8688 mL 1.7376 mL 3.4752 mL 4.344 mL
100 mM 0.0869 mL 0.4344 mL 0.8688 mL 1.7376 mL 2.172 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of Liquid Chromatography & Related Technologies, 2013, 36(17).
Thin-layer chromatographic evidence of proline peptidization in solution and its thin-layer chromatographic enantioseparation.[Reference: WebLink]
Direct enantioseparation of underivatized amino acids dissolved in the aqueous and nonaqueous solvents by means of the chiral TLC is a difficult analytical task. Most often such enantioseparations are carried out for the derivatized amino acids, or by means of the ion-exchange chromatography or electrophoresis. The main reasons of the aforementioned difficulty seem an ability of the chiral low molecular weight carboxylic acids (amino acids included) to undergo spontaneous condensation and spontaneous chiral conversion, as confirmed, for example, by the results of our earlier studies.
METHODS AND RESULTS:
In this study, we provide an experimental evidence of rapid peptidization of L-proline and DL-Proline obtained by means of the two different TLC systems, additionally confirmed by LC/MS and 1H NMR spectroscopy. Additionally, a novel TLC system for the direct enantioseparation of DL-Proline is proposed, which considerably outperforms earlier elaborated systems.
CONCLUSIONS:
Finally, relevant practical conclusions are drawn.
Crystengcomm, 2012, 14.
Effect of enantiomeric ratio and preparation method on proline crystal form[Reference: WebLink]

METHODS AND RESULTS:
Proline enantiomers were crystallized in a range of enantiomeric ratios and characterized by thermal methods, X-ray diffraction, and solid-state NMR spectroscopy to qualitatively and quantitatively characterize the resulting crystal forms. When crystallized by solvent evaporation or in the absence of enantiomeric excess, the observed racemic cocrystal consisted of only the previously published form,DL-Proline (form I). However, lyophilization of solutions containing enantiomeric excess resulted in the presence of a new, thermodynamically stable polymorph of the racemic cocrystal,DL-Proline form II. Both the enantiomeric ratio and crystallization method influenced the polymorphism of the racemic cocrystal.
CONCLUSIONS:
Due to the prevalence of chiral molecules and cocrystals among pharmaceuticals, this work has implications for current polymorphic screening methods.
Oxypeucedanin hydrate

Catalog No: CFN90557
CAS No: 2643-85-8
Price: $80/20mg
Glycitin

Catalog No: CFN99105
CAS No: 40246-10-4
Price: $70/20mg
Isoschaftoside

Catalog No: CFN92029
CAS No: 52012-29-0
Price: $118/20mg
Ganoderic acid K

Catalog No: CFN92057
CAS No: 104700-95-0
Price: $318/5mg
Perillen

Catalog No: CFN90862
CAS No: 539-52-6
Price: $168/20mg
(+)-Borneol

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Shionone

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Retronecine

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Gomisin A

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Clinopodiside A

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