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    Natural Products
    Dehydroheliobuphthalmin
    Information
    CAS No. 103001-05-4 Price
    Catalog No.CFN99046Purity>=98%
    Molecular Weight412.4 Type of CompoundLignans
    FormulaC22H20O8Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Dehydroheliobuphthalmin

    Dehydroheliobuphthalmin
    Product Name Dehydroheliobuphthalmin
    CAS No.: 103001-05-4
    Catalog No.: CFN99046
    Molecular Formula: C22H20O8
    Molecular Weight: 412.4 g/mol
    Purity: >=98%
    Type of Compound: Lignans
    Physical Desc.: Powder
    Source: The leaves of Platycladus orientalis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • J-STAGE2015, 249-255
  • Sci Rep.2020, 10:4495(2020)
  • Sci Adv.2018, 4(10)
  • J Nat Prod.2018, 81(4):966-975
  • Korean Journal of Pharmacognosy2018, 49(4):349-361
  • Evid Based Complement Alternat Med.2018, 2018:1073509
  • Food Research International2020, 108987
  • Industrial Crops and Products2017, 95:286-295
  • Journal of Functional Foods2017, 30:30-38
  • Nutrients.2020, 12(5):1242.
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Neuroprotection Compound Library
  • Lignans Compound Library
  • Biological Activity
    Description: Dehydroheliobuphthalmin has significant neuroprotective activities against glutamate- induced neurotoxicity.
    In vitro:
    Nat. Prod. Sci.,2008,14(3):167-70.
    Neuroprotective lignans from Biota orientalis leaves.[Reference: WebLink]

    METHODS AND RESULTS:
    We previously reported that 90% MeOH fraction of Biota orientalis leaves (L.) ENDL. had significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells. In the present study, (-)-savinin (1), (-)-hinokinin (2), Dehydroheliobuphthalmin (3) were isolated by bioactivity-guided fractionation from the 90% MeOH fraction.
    CONCLUSIONS:
    All three lignans had significant neuroprotective activities against glutamate-induced neurotoxicity at the concentrations ranging from 0.1 to 10.0 μM.
    Dehydroheliobuphthalmin Description
    Source: The leaves of Platycladus orientalis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.4248 mL 12.1242 mL 24.2483 mL 48.4966 mL 60.6208 mL
    5 mM 0.485 mL 2.4248 mL 4.8497 mL 9.6993 mL 12.1242 mL
    10 mM 0.2425 mL 1.2124 mL 2.4248 mL 4.8497 mL 6.0621 mL
    50 mM 0.0485 mL 0.2425 mL 0.485 mL 0.9699 mL 1.2124 mL
    100 mM 0.0242 mL 0.1212 mL 0.2425 mL 0.485 mL 0.6062 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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