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Ecdysterone 2,3:20,22-diacetonide
Information
CAS No. 22798-98-7 Price
Catalog No.CFN98230Purity>=98%
Molecular Weight560.8 Type of CompoundSteroids
FormulaC33H52O7Physical DescriptionCryst.
Download COA    MSDS    SDF    ManualSimilar structuralComparison (Web)  (SDF)
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    Ecdysterone 2,3:20,22-diacetonide

    Ecdysterone 2,3:20,22-diacetonide
    Product Name Ecdysterone 2,3:20,22-diacetonide
    CAS No.: 22798-98-7
    Catalog No.: CFN98230
    Molecular Formula: C33H52O7
    Molecular Weight: 560.8 g/mol
    Purity: >=98%
    Type of Compound: Steroids
    Physical Desc.: Cryst.
    Source: The roots of Cyanotis arachnoidea C. B. Clarke
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Download: COA    MSDS    SDF    Manual
    Similar structural: Comparison (Web)  (SDF)
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    product package
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
    Biological Activity
    Description: Due to the multi-drug resistance reversal activity of the less polar ecdysteroids, several new products( including 20-hydroxyecdysone,20-hydroxyecdysone 2,3;20,22-diacetonide) are promising for being tested against various cancer cell lines.
    Ecdysterone 2,3:20,22-diacetonide Description
    Source: The roots of Cyanotis arachnoidea C. B. Clarke
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7832 mL 8.9158 mL 17.8317 mL 35.6633 mL 44.5792 mL
    5 mM 0.3566 mL 1.7832 mL 3.5663 mL 7.1327 mL 8.9158 mL
    10 mM 0.1783 mL 0.8916 mL 1.7832 mL 3.5663 mL 4.4579 mL
    50 mM 0.0357 mL 0.1783 mL 0.3566 mL 0.7133 mL 0.8916 mL
    100 mM 0.0178 mL 0.0892 mL 0.1783 mL 0.3566 mL 0.4458 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Anticancer Res. 2012 Apr;32(4):1291-7.
    Rapid, laser-induced conversion of 20-hydroxyecdysone and its diacetonide -- experimental set-up of a system for photochemical transformation of bioactive substances.[Pubmed: 22493361]

    METHODS AND RESULTS:
    20-hydroxyecdysone (20E), the most common ecdysteroid in Nature, and the easily obtained derivative 20-hydroxyecdysone 2,3;20,22-diacetonide (20ED), at different concentrations, were exposed to a 266 nm laser beam at an energy level of 6.5 mJ for different periods of time and evaluated for fluorescence emission during the process of irradiation. The products of irradiation were scanned from 200 to 1500 nm and then subjected to one-dimensional and two-dimensional thin layer chromatography. During irradiation, progressive significant changes in the fluorescence emission spectra were noted for both compounds with time that were accompanied by changes in their UV-Vis spectra. Full conversion of both compounds was reached within 14 minutes, and both compounds yielded several major products and several minor ones representing a wide polarity range.
    CONCLUSIONS:
    The photo-transformation system described here was proven to be a useful and flexibly adjustable tool for the laser-catalyzed conversion of bioactive compounds. Due to the multi-drug resistance reversal activity of the less polar ecdysteroids, several new products are promising for being tested against various cancer cell lines. Fractionation, isolation and characterization of the irradiated products are currently in process.
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