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    Natural Products
    Ganoderic acid Df
    Ganoderic acid Df
    Information
    CAS No. N/A Price $318 / 5mg
    Catalog No.CFN95514Purity>=98%
    Molecular Weight516.7Type of CompoundTriterpenoids
    FormulaC30H44O7Physical DescriptionPowder
    Download COA    MSDSSimilar structuralComparison (Web)  (SDF)
    Citing Use of our Products
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    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $365.7 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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  • Package
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    Ganoderic acid Df

    Ganoderic acid Df
    Product Name Ganoderic acid Df
    CAS No.: N/A
    Catalog No.: CFN95514
    Molecular Formula: C30H44O7
    Molecular Weight: 516.7 g/mol
    Purity: >=98%
    Type of Compound: Triterpenoids
    Physical Desc.: Powder
    Source: The fruit body of Ganoderma lucidum
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $318 / 5mg
    Download: COA    MSDS
    Similar structural: Comparison (Web)  (SDF)
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  • Biomed Pharmacother.2019, 116:108987
  • Nutrients.2018, 10(7)
  • National University of Pharmacy2022, 1:73-76
  • Tokyo Pharmaceutical University2020, 500001431953.
  • Front Plant Sci.2022, 12:811166.
  • Oxid Med Cell Longev.2020, 2020:8887251.
  • J Sci Food Agric.2018, 98(3):1153-1161
  • Sci Rep.2017, 7:40345
  • Molecules.2019, 24(2):E343
  • Chin J Pharm Anal.2019, 39(7):1217-1228
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Triterpenoids Compound Library
  • Biological Activity
    Description: Ganoderic acid Df exhibited potent human aldose reductase inhibitory activity, with an IC(50) of 22.8 μM in vitro. Ganoderic acid Df as a potential anticancer agent.
    In vitro:
    Fitoterapia . 2010 Dec;81(8):1033-1036.
    Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum[Pubmed: 20603199]
    Ganoderic acid Df, a new lanostane-type triterpenoid, was isolated from the fruiting body of Ganoderma lucidum. Its structure was characterized as 7β, 11β-dihydroxy-3, 15, 23-trioxo-5α-lanosta-8-en-26-oic acid by 1D- and 2D-NMR spectra. This compound exhibited potent human aldose reductase inhibitory activity, with an IC(50) of 22.8 μM in vitro. A carboxyl group of this compound's side chain is essential for eliciting inhibitory activity because its methyl ester is much less active.
    Ganoderic acid Df Description
    Source: The fruit body of Ganoderma lucidum
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9354 mL 9.6768 mL 19.3536 mL 38.7072 mL 48.384 mL
    5 mM 0.3871 mL 1.9354 mL 3.8707 mL 7.7414 mL 9.6768 mL
    10 mM 0.1935 mL 0.9677 mL 1.9354 mL 3.8707 mL 4.8384 mL
    50 mM 0.0387 mL 0.1935 mL 0.3871 mL 0.7741 mL 0.9677 mL
    100 mM 0.0194 mL 0.0968 mL 0.1935 mL 0.3871 mL 0.4838 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Fitoterapia . 2010 Dec;81(8):1033-1036.
    Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum[Pubmed: 20603199]
    Ganoderic acid Df, a new lanostane-type triterpenoid, was isolated from the fruiting body of Ganoderma lucidum. Its structure was characterized as 7β, 11β-dihydroxy-3, 15, 23-trioxo-5α-lanosta-8-en-26-oic acid by 1D- and 2D-NMR spectra. This compound exhibited potent human aldose reductase inhibitory activity, with an IC(50) of 22.8 μM in vitro. A carboxyl group of this compound's side chain is essential for eliciting inhibitory activity because its methyl ester is much less active.
    Salvigenin

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