ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $125.4 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
J Biol Chem.2014, 289(3):1723-31Pharmacogn Mag.2015, 11:S585-91The Journal of Internal Korean Me...2015...Ind Crops Prod.2015, 67:185-191J Pharm Biomed Anal.2016, 129:50-59Pharm Biol.2016, 54(7):1255-62Polytechnic University of Catalon...2017...J. of The Korean Society of Food ...2017...
J Chromatogr A.2017, 1518:46-58Tropical J. of Pha. Research...2017...Molecules.2017, 22(12)Cell Physiol Biochem....2017...Phytother Res.2018, 32(5):923-932J Liq Chromatogr R T...2018...Phytomedicine.2019, 57:95-104Phytomedicine.2019, 61:152813
J Nat Prod.2019, 82(4):1002-1008Planta Med.2019, 85(3):217-224J Chromatogr B Analyt Technol Bio...2020...Int J Biol Macromol.2020, 169:342-351J Insect Sci.2020, 20(5):18. Biomed Sci Letters.2020, 26:319-326Analytical Letters.2020, doi 10.1008
Our products had been exported to the following research institutions and universities, And still growing.
Nanjing University of Chinese M... (China)Kazusa DNA Research Institute (Japan)University of Malaya (Malaysia)Deutsches Krebsforschungszentrum (Germany)
University of Melbourne (Australia)Instytut Nawozów Sztucznych w ... (Poland)Universidad Miguel Hernández (Spain)National Cancer Center Research... (Japan)
Univerzita Karlova v Praze (Czech Republic)Universiti Kebangsaan Malaysia (Malaysia)MTT Agrifood Research Finland (Finland)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Breast Cancer.2015, 18(2):112-118Phytomedicine.2015, 22(14):1262-8J of the Korean Society of Cosmetics and Cosmetology2018, 399-406Antimicrob Agents Chemother.2020, AAC.01921-20.Chung Shan Medical University2020, US20200323790A1Biology (Basel).2020, 9(11):363. Molecules.2019, 24(7):E1290J Food Compos Anal2017, 62:197-204RSC Adv.2018, 32621-32636BMC Complement Altern Med.2018, 18(1):303
Related Screening Libraries
|| Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range. |
||Estrogen receptor | Progestogen receptor|
|Plos One, 2014, 9(6):e98559. |
|Isolation of Antiosteoporotic Compounds from Seeds of Sophora japonica.[Pubmed: 24892557]|
|Chemical investigation of Sophora japonica seeds resulted in the isolation of seven metabolites identified as: genistin (1), sophoricoside (2), sophorabioside (3), sophoraflavonoloside (4), Genistein 7,4'-di-O-beta-D-glucopyranoside (5), kaempferol 3-O-α-L-rhamnopyranosyl(1 → 6)β-D-glucopyranosyl(1 → 2)β-D-glucopyranoside (6) and rutin (7).
METHODS AND RESULTS:
Compounds 1, 2 and 5 showed significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range. Compounds 1 and 2 showed minimal cell membrane damaging effect using LDH leakage assay. Accordingly, compound 2 (sophoricoside, (SPH)) was selected for further in-vivo studies as a potential anti-osteoporosis agent. The anti-osteoporotic effect of SPH was assessed in ovarectomized (OVX) rats after oral administration (15 mg/kg and 30 mg/kg) for 45 days compared to estradiol (10 µg/kg) as a positive control. Only in a dose of 30 mg/kg, SPH regained the original mechanical bone hardness compared to normal non-osteoporotic group. However, SPH (15 mg/kg) significantly increased the level of alkaline phosphatase (ALP) to normal level. Treatment with SPH (30 mg/kg) increased the level of ALP to be higher than normal group. SPH (15 mg/kg) did not significantly increase the serum level of osteocalcin (OC) compared to OVX group. On the other hand, treatment with SPH (30 mg/kg) significantly increased the level of OC to 78% higher than normal non-ovarectomized animals group. In addition, SPH (15 mg/kg) decreased the bone resorption marker, acid phosphatase (ACP) to normal level and SPH (30 mg/kg) further diminished the level of serum ACP.
Histopathologically, sophoricoside ameliorated the ovarectomy induced osteoporosis in a dose dependent manner. The drug showed thicker bony trabeculae, more osteoid, and more osteoblastic rimming compared to OVX group.
Genistein 7,4'-di-O-beta-D-glucopyranoside Description
||The aerial parts of Lupinus hartwegi.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Phytochemistry. 2003 Jun;63(4):449-52. |
|Flavone C-glycosides from Lupinus hartwegii.[Pubmed: 12770596]|
METHODS AND RESULTS:
From the aerial parts of Lupinus hartwegii, two new flavone C-glycosides apigenin-7-O-beta-apiofuranosyl-6, 8-di-C-beta-glucopyranoside (1) and apigenin-7-O-beta-apiofuranosyl-6-C-beta-glucopyranosyl-8-C-(6z.qprime;-O-E-feruloyl)- beta-glucopyranoside (2) have been isolated together with two known isoflavonoid glucosides genistein-7-O-beta-glucopyranoside (3) and Genistein 7,4'-di-O-beta-D-glucopyranoside(4) as well as two known compounds ferulic acid 4-O-beta-glucopyranoside (5) and sparteine (6).
The structures of the isolated compounds were verified by means of MS and NMR spectral analyses.